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Preparation method of recombinant panda IL-2 immune adjuvant

An IL-2, immune adjuvant technology, applied in the biological field, can solve the problems of poor safety, unsatisfactory vaccines, and low immune efficiency

Inactive Publication Date: 2014-01-15
四川卧龙国家级自然保护区管理局 +1
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  • Summary
  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

Vaccine immunization is currently the main measure to prevent and control CDV, but the vaccines currently used are not very ideal, and there are two major problems of low immunization efficiency and poor safety

Method used

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  • Preparation method of recombinant panda IL-2 immune adjuvant
  • Preparation method of recombinant panda IL-2 immune adjuvant
  • Preparation method of recombinant panda IL-2 immune adjuvant

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Experimental program
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Embodiment Construction

[0052] The present invention will be described in detail below in conjunction with specific embodiments.

[0053] 1. Cloning of the whole gene of giant panda IL-2

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Abstract

The invention discloses a preparation method of a recombinant panda IL-2 immune adjuvant. The recombinant panda IL-2 immune adjuvant is a recombinant panda IL-2 (gpIL-2) immune adjuvant, which has a prominent effect and a convenient extraction process, can be directly applied to production and clinical application, improves the immune effect of canine distemper vaccine strain and other conventional vaccines, controls the occurrence and epidemic of diseases, and protects the health of panda. Canine distemper is usually known as "the fatal infectious disease", has become the first fulminating infectious disease that threatens the species number and life safety of pandas, and badly affects the healthy development of pandas. The recombinant panda IL-2 (gpIL-2) immune adjuvant can prominently strengthen the immune effect of canine distemper vaccine strain, and has an important meaning on preventing and treating of canine distemper.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to a preparation method of a recombinant giant panda IL-2 (gpIL-2) immune adjuvant. Background technique [0002] The giant panda is known as China's "national treasure" and is a world-class rare wild animal. However, it is on the verge of extinction. In addition to the destruction of the giant panda's habitat due to human factors, disease and death have become one of the key reasons for the current endangered giant panda population. Among the more than 40 kinds of diseases that giant pandas suffer from, canine distemper is the most severe infectious disease that threatens the population and life safety of giant pandas. Vaccine immunization is currently the main measure to prevent and control CDV, but the vaccines currently used are not very ideal, and there are two problems of low immunization efficiency and poor safety. Therefore, improving the immunity of giant pandas under safe dos...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N15/70A61K39/39
Inventor 李德生朱玲张和民王承东易悦刘骁
Owner 四川卧龙国家级自然保护区管理局
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