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Detector for coagulation function of whole blood and detection method

A function detection and detection instrument technology, which is applied in the field of clinical medical examination, can solve the problems of easy interference, cumbersome operation, poor repeatability, etc., and achieve the effect of improving detection efficiency, obvious detection signal and low cost

Active Publication Date: 2014-01-01
SINNOWA MEDICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These instruments or methods have certain defects or deficiencies due to cumbersome operation, poor repeatability, easy interference, or high cost.

Method used

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  • Detector for coagulation function of whole blood and detection method
  • Detector for coagulation function of whole blood and detection method
  • Detector for coagulation function of whole blood and detection method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Such as Figure 1 ~ Figure 3 As shown, this embodiment discloses a novel whole blood coagulation function tester, including a test vessel 6 , a test vessel driver 1 , a long-wave light source 8 , a light wave receiver 9 , and a test station 3 with a heating function. The detection vessel 6 , the long-wave light source 8 , the light wave receiver 9 and the detection position 3 with a heating function are arranged in a light-tight casing (not shown in the figure). In this embodiment, the long-wave light source 8 adopts a light wave generator with a wavelength of 840 nm. The detection vessel 6 is at an angle of 30 degrees to the ground plane, and the blood samples are unevenly distributed in the detection vessel. The connection 2 between the detection vessel 6 and the detection vessel driver 1 is the detection vessel drive device. The rotational speed of the detection vessel driver 1 is set at a constant rate of 2 seconds per revolution. The detection vessel 6 is driven ...

Embodiment 2

[0060] The detector structure of this embodiment is the same as that of Embodiment 1.

[0061] Such as Figure 1 ~ Figure 3 As shown, the detection method steps of the present embodiment are as follows:

[0062] a) Collect the patient's whole blood sample into the detection vessel 6 and add 5 ceramic particles with a diameter of 2mm that are impermeable to long waves (waves above 700nm), but do not dilute the blood sample;

[0063] b) The blood sample 5 in the detection vessel 6 is slightly mixed with the added particles 4 and then placed in the detection position 3 with a heating function;

[0064]c) Turn on the switch to make the detection vessel 5 rotate along its own central axis. The uncoagulated blood sample is mainly distributed at the lowest point of the detection vessel at this time, and the particles 4 that are impermeable to long waves also settle at the bottom of the detection vessel before the blood sample is not coagulated because the specific gravity is greater...

Embodiment 3

[0084] The difference between the whole blood coagulation function detector of the device described in this embodiment and that of Embodiment 1 is that the light wave generator and the light wave receiver are oppositely arranged on the upper and lower sides of the detection vessel, and the light wave emission and detection optical path are initially Just separated by the central area of ​​the blood sample to be tested, the added particles are iron metal particles with a diameter of 1 mm and a chrome-plated surface. When the blood sample is not coagulated, the light wave receiver cannot or can only receive the weak light emitted by the light wave generator during the rotation process of the detection vessel. At this time, the light wave receiver shows that the measured signal is 0-10mV; In the first period of rotation of the detection vessel after blood coagulation, the light wave receiver can obviously receive the light emitted by the light wave generator, and the maximum signa...

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Abstract

The invention discloses a detector for the coagulation function of whole blood. The detector comprises a detecting vessel, a rotating device, a light wave generator, a light wave receiver, a timer and a shell, wherein the detecting vessel is used for placing the whole blood; the rotating device, the light wave generator, the light wave receiver, the timer and the shell are connected with the detecting vessel; the rotating device is used for driving the detecting vessel to rotate around the self central axis; the light wave generator and the light wave receiver are oppositely arranged on the two sides of the detecting vessel; when the whole blood inside the detecting vessel is not coagulated, the light wave receiver always receives the quite strong light emitted by the light wave generator continuously, cannot or can only receive the weak light signal emitted by the light wave generator in the rotation process of the detecting vessel; and the timer is used for recording the time that the light wave receiver, into which a coagulation reagent is added, cannot receive the light emitted by the light wave generator for the first time or cannot stably receive the light emitted by the light wave generator, or the time that the light wave receiver receives the quite strong light signal for the first time. The invention also discloses a method for detecting the coagulation function of the whole blood.

Description

technical field [0001] The invention relates to the field of clinical medical testing, in particular to a detection instrument and a detection method for whole blood coagulation function, especially coagulation time, using whole blood as a sample. Background technique [0002] The coagulation function of blood is an important function of blood, which is generally evaluated by the length of time from the addition of coagulation reagents to the formation of coagulation in the sample. Excessive blood coagulation function can easily lead to thrombosis, and low blood coagulation function is prone to bleeding disorders. Therefore, the detection and evaluation of blood coagulation function is of great significance in clinical medicine. At present, there are many kinds of coagulation function detection instruments, but most of the blood coagulation function tests are realized through the detection of separated plasma. However, the plasma separation process takes a certain amount o...

Claims

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Application Information

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IPC IPC(8): G01N21/17
Inventor 徐新朱建波周强曹宁宋成桥
Owner SINNOWA MEDICAL SCI & TECH
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