Clarithromycin capsule and preparation method thereof
A technology of clarithromycin and production method, which is applied in capsule delivery, pharmaceutical formula, medical preparations of non-active ingredients, etc., and can solve problems such as difficulty in finding parameters and changes
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[0014] The internal components of clarithromycin capsules are composed of clarithromycin with a weight ratio of 250:0.75:20:0.5, sodium lauryl sulfate as a cosolvent, polyethylene glycol 6000 as a binder and filler, as The glidant consists of magnesium stearate.
[0015] Get clarithromycin 250g, sodium lauryl sulfate 0.75g, macrogol 6000 20g, magnesium stearate 0.5g, make 1000 clarithromycin capsules.
[0016] During preparation: take the clarithromycin raw material of the prescribed amount, mix it with polyethylene glycol 6000 and sodium lauryl sulfate in the prescribed amount, melt and granulate it, mix the granules with magnesium stearate evenly, and fill it into hollow capsules ; After polishing the residual powder on the shell of the capsule, the finished product is packaged.
[0017] Technological process: 1. Raw materials and auxiliary materials - batching, weighing, 2. Granulation - whole grains, blending, 3. Granules - filling, polishing (inspection), 4. Bulk capsule...
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