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Bronchitis tablet film-coated tablet and preparation method thereof

A technology for bronchitis tablets and film-coated tablets, which is applied to the field of bronchitis tablets and film-coated tablets and the preparation thereof, can solve the problems of long heating time of core drugs, increase product production costs, health hazards of production workers, and the like, and achieve improved bioavailability. , Improve the quality standard, the effect of environmental protection

Active Publication Date: 2019-03-05
JIUZHITANG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the bronchitis tablets currently used clinically are sugar-coated tablets. During the drying process, the drying speed is slow, and the core drug is heated for a long time, which will affect the quality of the drug. The production process is long and complicated, and a large amount of syrup is required for sugar-coating and talcum powder, which increase the production cost of the product, easily cause production environmental pollution and cause harm to the health of production workers. The sugar-coated tablets of bronchitis tablets are unacceptable to diabetic patients, which limits its scope of application

Method used

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  • Bronchitis tablet film-coated tablet and preparation method thereof
  • Bronchitis tablet film-coated tablet and preparation method thereof
  • Bronchitis tablet film-coated tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0010] A bronchitis tablet film-coated tablet, the bronchitis tablet film-coated tablet refers to the bronchitis tablet formed by spraying a water-soluble film coating material on the surface of the bronchitis plain tablet.

[0011] Prepare the preparation method of above-mentioned bronchitis tablet film-coated tablet, its steps are as follows:

[0012] (1) Preparation of film coating solution: put 2.5kg of film coating powder in the slurry mixing tank, add 13.2kg of purified water, prepare water-soluble film coating solution, stir evenly, and set aside;

[0013] (2) Film coating: put 50kg of pressed bronchitis tablets in the coating pot, turn on the hot air, and turn the host to make the bronchitis tablets roll in the coating pot, and the temperature gradually rises to 40~ At 60°C, start the exhaust and dust collection device to heat the plain tablets evenly, start the air compressor, turn on the spray gun, adjust the atomization pressure to 0.12-0.15Mpa, and the speed of the...

Embodiment 2

[0015] A bronchitis tablet film-coated tablet, the bronchitis tablet film-coated tablet refers to the bronchitis tablet formed by spraying a water-soluble film coating material on the surface of the bronchitis plain tablet.

[0016] Prepare the preparation method of above-mentioned bronchitis tablet film-coated tablet, its steps are as follows:

[0017] (1) Preparation of film coating solution: put 2.5kg of film coating powder in the slurry mixing tank, add 14kg of purified water to prepare water-soluble film coating solution, stir evenly, and set aside;

[0018] (2) Film coating: put 50kg of pressed bronchitis tablets in the coating pot, turn on the hot air, and turn the host to make the bronchitis tablets roll in the coating pot, and the temperature gradually rises to 50~ At 60°C, start the exhaust and dust collection device to heat the plain tablets evenly, start the air compressor, turn on the spray gun, adjust the atomization pressure to 0.12-0.15Mpa, and the speed of the...

Embodiment 3

[0020] A bronchitis tablet film-coated tablet, the bronchitis tablet film-coated tablet refers to the bronchitis tablet formed by spraying a water-soluble film coating material on the surface of the bronchitis plain tablet.

[0021] Prepare the preparation method of above-mentioned bronchitis tablet film-coated tablet, its steps are as follows:

[0022] (1) Prepare film-coating solution: put 2.5kg of film-coating powder in the mixing tank, add 12kg of purified water to prepare water-soluble film-coating solution, stir evenly, and set aside;

[0023] (2) Film coating: put 50kg of pressed bronchitis tablets in the coating pot, turn on the hot air, and turn the host to make the bronchitis tablets roll in the coating pot, and the temperature gradually rises to 40~ 50°C, start the exhaust and dust suction device to make the plain tablets heated evenly, start the air compressor, turn on the spray gun, adjust the atomization pressure to 0.12-0.15Mpa, and the speed of the coating pan ...

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Abstract

The invention discloses a bronchitis film-coated tablet and a preparation method thereof. The bronchitis film-coated tablet is a bronchitis tablet which is formed by coating a water soluble film coating material on the surface of a bronchitis bare tablet in a mist way, and the preparation method of the bronchitis film-coated tablet comprises the technology processes such as film coating liquid preparation and film coating wrapping. Compared with the bronchitis tablet in the prior art, the bronchitis film-coated tablet prepared by the invention has the following advantages that used auxiliary materials are few, the production cost is reduced, the tablet breakage is reduced, the productive rate is improved, the production time is greatly shortened, environment protection is facilitated, the appearance form of the tablet is improved, the humidity resistance is good, the medicine stability is improved, the dissolution rate of the tablet is improved, the tablet can be rapidly disintegrated, the effect is taken rapidly, the prepared tablet is widened in applicative population and is particularly applicative to diabetic patients, and the quality control is facilitated through improving the quality standards.

Description

technical field [0001] The invention belongs to the technical field of medicines, and mainly relates to a film-coated bronchitis tablet and a preparation method thereof. Background technique [0002] Bronchitis Tablets are composed of four traditional Chinese medicines such as Aidicha, Jiuscutellaria, Earthworm, and Licorice. Most of the bronchitis tablets currently used clinically are sugar-coated tablets. During the drying process, the drying speed is slow, and the core drug is heated for a long time, which will affect the quality of the drug. The production process is long and complicated, and a large amount of syrup is required for sugar-coating And talcum powder increases the production cost of the product, easily causes production environmental pollution and produces hazards to the health of production workers. The sugar-coated tablets of bronchitis tablets are unacceptable for diabetics, resulting in limited scope of application. Contents of the invention [0003] ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61J3/00A61K36/539A61K9/28A61P11/00A61P11/06A61K35/56A61K35/62
Inventor 周芳谷陟欣欧金秀张妮瑜颜冬兰辛秀朱丽袁莉陈诗圣
Owner JIUZHITANG
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