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Topical pharmaceutical composition for preventing and treating canine acariasis disease and preparation method thereof

A technology of externally used drugs and compositions, which is applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, etc., which can solve problems such as high prices, inability to use large quantities, and inability to use collies, etc., to achieve low toxicity, Improves the extraction rate and enhances the effect of percutaneous absorption

Active Publication Date: 2015-03-25
ZHENGZHOU BARY ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is that the method of injecting ivermectin is mainly adopted for the prevention and treatment of mites in dogs, but ivermectin is invalid for mites in the egg stage and needs to be used for a long time, and ivermectin Bacterin has strong toxicity, cannot be used in large quantities, cannot be used for collie dogs, and the price is relatively high, it is only suitable for pet dogs, not for other purposes

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The embodiment of the present invention provides an external pharmaceutical composition for preventing and treating canine acariasis, which is composed of the following raw materials: 100g of fennel, 50g of Huoxiang, 100g of Veratrum, 50g of Sophora flavescens, 50g of camphor leaves, 100g of Garcinia cambogia, Viola 50g and mint 100g.

[0022] The embodiment of the present invention also provides a preparation method of an external pharmaceutical composition for preventing and treating canine mite, comprising the following steps:

[0023] (1) Alcohol extraction step: Take 100g of fennel, 50g of Huoxiang, 100g of veratrum, 50g of Sophora flavescens, 50g of camphor leaves, 100g of Garcinia cambogia, 50g of viola and 100g of mint, and mix the raw materials into percolation In the extraction tank, add 80% ethanol to the percolation extraction tank, the amount of ethanol added is twice the total weight of the mixed raw medicinal materials, soak for 6 hours, then add 80% etha...

Embodiment 2

[0027] The embodiment of the present invention provides an external pharmaceutical composition for preventing and treating canine acariasis, which is composed of raw materials: 300g fennel, 200g ageratum, 300g veratrum, 150g sophora flavescens, 150g camphor leaf, 300g gamboge, Viola 200g and mint 300g.

[0028] The embodiment of the present invention also provides a preparation method of an external pharmaceutical composition for preventing and treating canine mite, comprising the following steps:

[0029] (1) Alcohol extraction step: Take 300g of fennel, 200g of Huoxiang, 300g of veratrum, 150g of Sophora flavescens, 150g of camphor leaves, 300g of Garcinia cambogia, 200g of viola and 300g of mint, and mix the raw materials into percolation In the extraction tank, add 95% ethanol to the percolation extraction tank, the amount of ethanol added is 5 times the total weight of the mixed raw medicinal materials, soak for 12 hours, then add 95% ethanol, percolation extraction, unti...

Embodiment 3

[0033] The embodiment of the present invention provides an external pharmaceutical composition for preventing and treating canine acariasis, which is composed of the following raw materials: 200g fennel, 125g ageratum, 200g veratrum, 100g sophora flavescens, 100g camphor leaves, 200g gamboge, Viola 125g and mint 200g.

[0034] The embodiment of the present invention also provides a preparation method of an external pharmaceutical composition for preventing and treating canine mite, comprising the following steps:

[0035](1) Alcohol extraction step: Take 200g of fennel, 125g of Huoxiang, 200g of Veratrum, 100g of Sophora flavescens, 100g of camphor tree leaves, 200g of Garcinia Cambogia, 125g of Viola Viola and 200g of mint, and mix the raw materials into percolation In the extraction tank, add 90% ethanol to the percolation extraction tank, the amount of ethanol added is 4 times the total weight of the mixed raw medicinal materials, soak for 9 hours, then add 90% ethanol, per...

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PUM

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Abstract

The invention discloses a topical pharmaceutical composition for preventing and treating a canine acariasis disease and a preparation method thereof. The topical pharmaceutical composition comprises the following raw medicinal materials in parts by weight: 10-30 parts of fennel, 5-20 parts of wrinkled giant hyssop, 10-30 parts of black false hellebore, 5-15 parts of radix sophorae flavescentis, 5-15 parts of camphortree leaf, 10-30 parts of gamboges, 5-20 parts of Chinese violet and 10-30 parts of mint. The preparation method comprises the steps of alcohol extraction of a liquid medicine, concentration of an extract, and a preparation technology. The topical pharmaceutical composition has the beneficial effects that the characteristics of the medicament are combined on the basis of modern Chinese medicine research; the alcohol extraction technology is adopted aiming at the symptoms of the canine acariasis disease and excited bacterial infection; the extraction rate of the effective ingredients is improved; the percutaneous absorption ability of the medicament is enhanced by adopting a scientific preparation technology; the external Chinese medicine preparation for a dog is prepared; and acarids in endothelium and epidermis of the dog are completely killed. Compared with the traditional therapeutic medicament, the topical pharmaceutical composition has the advantages of being low in toxicity and suitable for all kinds of dogs.

Description

technical field [0001] The invention relates to a traditional Chinese veterinary medicine for dogs, in particular to a pharmaceutical composition for external use and a preparation method thereof for preventing and treating skin diseases such as hair loss, dermatitis and infection in dogs caused by mites and the like. Background technique [0002] Canine acariasis is a common skin disease in dogs, a chronic parasitic skin disease of dogs caused by mites. Features: Dogs are characterized by severe itching, hair loss and dermatitis. The symptoms are mostly chronic dermatitis, itching, hair loss on the affected part, scabs and a foul smell all over the body. Although it is not a fatal disease, the course of the disease is long. If it is not properly diagnosed and treated, it may aggravate the condition or cause secondary infection of other diseases, leading to more serious consequences and bringing certain difficulties to the treatment. Mites are more common in winter, late au...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61P33/14A61P17/00
Inventor 勾陈松
Owner ZHENGZHOU BARY ANIMAL PHARMA
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