Device and method for detecting biological tissue of pressure modulation near infrared spectrum

Abstract

The invention discloses a device and a method for detecting biological tissue of pressure modulation near infrared spectrum. Biological tissue physiological status judgment and volume difference spectrum measurement are achieved according to pressure and spectrum measuring results in the process of deformation of the biological tissue: changing of biological tissue diffuse reflection spectrum along with the pressure and action time is respectively measured, multiplicative scatter correction and second derivative processing are conducted to the measured spectrum, content change of free water and bound water is obtained, fitting processing is conducted to the content change of the free water and the bound water, the pressure and the action time, biological tissue status is judged according to a fitting curve trend; differential treatment is conducted to diffuse reflection spectrum obtained under different pressure values, the water content change in the tissue is taken as a reference, physiological background of the tissue is deducted, and spectrum net analyte signals of tissue elements are obtained. According to method for detecting the biological tissue of the pressure modulation near infrared spectrum, rapid detecting of physiological status of the biological tissue is achieved, and spectrum detection accuracy of the tissue elements is improved.

Description

technical field [0001] The present invention relates to a device and method for measuring properties and components of biological tissue. In particular, it relates to a device and method for pressure-modulated near-infrared spectroscopy to realize biological tissue detection. Background technique [0002] The main components of biological tissue include protein, fat, water, etc., and the water in the tissue accounts for about 70% of the total volume of the biological tissue. basis. In the study of non-destructive testing of biological tissue components and physiological and pathological states, the mechanical and optical properties of biological tissue are closely related to the physiological morphology and function of biological tissue. By measuring the mechanical and optical parameters of biological tissue, not only can biological tissue For the diagnosis of physiological state, the specific content of various components can also be measured. In previous studies, differ...

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Problems solved by technology

In addition, during the measurement process, the differences between individuals or different parts of the same individual and the inaccurate positioning of the measurement parts can also easily cause measurement spectrum errors and affect the accuracy of modeling predictions.

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