Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Rhiaoma iridis tectori capsule detecting method

A detection method, Chuanshegan technology, applied in the direction of measuring devices, instruments, scientific instruments, etc., to achieve the effect of protecting health, ensuring the quality of medicines, and avoiding mixing

Active Publication Date: 2014-12-24
SICHUAN FENGCHUN PHARMA
View PDF5 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Aiming at the defects of the existing detection methods, the present invention formulates a related more scientific and effective detection method. In addition to the inspection of general items in accordance with the general principles of the Pharmacopoeia, the present invention also increases the thinness of the active ingredients Sheganxin B and Shegan aglycone. Layer identification, a thin-layer identification of hirsutin, to ensure that the drug Chuanshegan capsules contain sheganoside, sheganxin glycoside B and shegan aglycone, but not hirsutin

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] 【 method 】Take Chuanshegan total flavonoids, pulverize into fine powder, add appropriate amount of auxiliary materials, put into capsules, and make 1000 capsules to obtain.

[0034] 【 character 】This product is a hard capsule, the content is brownish yellow, with a slightly pungent smell and a bitter taste.

[0035] 【 identify 】Identification of Shegan glycoside, Sheganxin glycoside B, Shegan aglycone, and Radixin

[0036]Take 3 mg of the content of this product and place it in a 5ml volumetric flask, dissolve it with 60% to 80% ethanol and dilute to the mark, shake well, and use it as the test solution. Each 2 mg root root reference substance is placed in a 5ml volumetric flask, dissolved with 60-80% ethanol and diluted to the mark, shaken up, and used as a mixed solution of the reference substance, according to thin-layer chromatography, absorb the test solution and the reference substance Mix 5 μl each, and spot on the same silica gel GF 254 On a thin-layer b...

Embodiment 2

[0046] 【 method 】Take Chuanshegan total flavonoids, pulverize into fine powder, add appropriate amount of auxiliary materials, put into capsules, and make 1000 capsules to obtain.

[0047] 【 character 】This product is a hard capsule, the content is brownish yellow, with a slightly pungent smell and a bitter taste.

[0048] 【 identify 】Identification of Shegan glycoside, Sheganxin glycoside B, Shegan aglycone, and Radixin

[0049] Take 7mg of the content of this product and place it in a 5ml volumetric flask, dissolve it with 60%-80% ethanol and dilute to the mark, shake well, and use it as the test solution. Each 2 mg root root reference substance is placed in a 5ml volumetric flask, dissolved with 60-80% ethanol and diluted to the mark, shaken up, and used as a mixed solution of the reference substance, according to thin-layer chromatography, absorb the test solution and the reference substance Mix 5-10 μl of each solution, and spot on the same silica gel GF 254 On a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a rhiaoma iridis tectori capsule detecting method. The detecting method comprises the steps of distinguishing and content determination, wherein the distinguishing step includes distinguishing on tectoridin, novel tectoridin B, blackberry lily aglycone and a Japanese dock root element in capsules, and the content determination step includes content determination on the tectoridin and the blackberry lily aglycone in the capsules. The scientific and effective detecting method aims at overcoming the defect of existing detecting methods, further comprises the steps of distinguishing thin layers of the effective ingredient novel tectoridin B and the blackberry lily aglycone and distinguishing a thin layer of the Japanese dock root element except common program checking steps according to pharmacopeia general rules, and ensures the rhiaoma iridis tectori capsules to contain the tectoridin, the novel tectoridin B and the blackberry lily aglycone and not to contain the Japanese dock root element. In addition, the rhiaoma iridis tectori capsule detecting method adopts high efficiency liquid chromatography, inspects two effective ingredients with high contents, namely the tectoridin and the blackberry lily aglycone in the capsules in one time by means of a mode that the same mobile phases of the ingredients are subjected to gradient elution, and enables the contents of important ingredients to be effectively monitored.

Description

technical field [0001] The invention relates to a method for detecting active ingredients in traditional Chinese medicine prescriptions, in particular to a method for detecting effective ingredients in Chuanshegan capsules. Background technique [0002] Chuanshegan Capsule is a hard capsule made by crushing the total flavonoids of Chuanshegan into fine powder, adding appropriate amount of excipients, and filling it into a capsule. It is a pure traditional Chinese medicine preparation. Shegan aglycone and so on. It has the functions of clearing away heat and detoxification, reducing swelling and relieving sore throat. It has a good curative effect on treating acute pharyngitis, laryngitis and acute upper respiratory tract infection caused by sore throat, hoarseness, and cough with yellow sputum. Now Chuanshegan Capsules are widely used clinically to treat acute pharyngitis, laryngitis and acute upper respiratory tract infection caused by sore throat, hoarseness, cough and y...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01N30/90G01N30/02
Inventor 钟茂团黎勇吴诗惠何德中
Owner SICHUAN FENGCHUN PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com