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Measure and control device for electrorotation biological chip experiment and experiment system

A technology of rotating organisms and measurement and control devices, which is applied in the direction of measuring devices, individual particle analysis, scientific instruments, etc., can solve the problems of complex structure of instruments, isolation of dedicated multi-phase broadband synchronous power supply, and obstacles to the development of biochip industry, etc., to achieve low cost, Meet the effect of miniaturization

Inactive Publication Date: 2013-04-17
CHINA JILIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 1. There is no perfect automated test measurement and control system;
[0006] 2. The integrated and systematically designed test platform is blank at home and abroad;
[0007] 3. The dedicated multi-phase broadband synchronous power supply is too isolated to achieve centralized and unified management with other components of the test platform;
[0008] 4. The automatic detection technology based on PC (or embedded system) image processing has not been realized to replace the existing human eye detection method
[0012] In addition, the electrospin biochip test platform, which uses a combination of computer and imaging device, also restricts the application range of biochips and hinders the development of biochip industry due to its complex instrument structure and overly specialized system operation (Hu Xiangyu ,, Tang Xiaoping, Yan Wei, etc.

Method used

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  • Measure and control device for electrorotation biological chip experiment and experiment system
  • Measure and control device for electrorotation biological chip experiment and experiment system
  • Measure and control device for electrorotation biological chip experiment and experiment system

Examples

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Embodiment Construction

[0061] The electrorotation biochip integrated test system and measurement and control device of the present invention will be further described below in the form of an example with reference to the accompanying drawings.

[0062] This example is preferably based on the DSP system to design the measurement and control device, the principle of the whole electrorotation biochip integrated test system is as follows figure 2 shown. Among them, the four-phase broadband synchronous power supply is used as the driving power for the electrorotation biochip experiment, and the microscopic camera system (composed of optical microscopic magnification devices and industrial cameras) takes images of the electrorotation biochip in the experiment, and the formed video data Output to the DSP system (measurement and control device), the DSP system simultaneously controls the parameters of the power signal output by the four-phase broadband synchronous power supply (voltage phase and conversion...

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Abstract

The invention discloses an integrated experiment device for an electrorotation biological chip experiment. According to the invention, An experiment system comprises a biological chip experiment operation platform, an electrorotation drive power supply, a microscopic camera system composed of an optical microscope amplification device and an industrial camera, a measurement and control device, and an input display device, wherein the measurement and control device is respectively connected with the microscopic camera system, the electrorotation drive power supply and the input display device; and the output end of the electrorotation drive power supply is connected with a power supply connector of the biological chip experiment operation platform. According to the technical scheme, the microscopic camera system and the drive power supply are relatively independent, the special measurement and control device which replaces a conventional PC machine and a capture card integrates the functions of collecting and processing of image information of the microscopic camera system, and controls the microscopic camera system to take images and the drive power supply to output all parameters of signals; and the whole-process automation of the electrorotation biological chip experiment is realized. Therefore, the development requirements of miniaturization, integration and intelligentization of biological chip experiment equipment are met.

Description

technical field [0001] The invention belongs to the field of automatic measurement and control and biotechnology, and relates to a technology for monitoring and controlling an electrorotation test, in particular to a biological chip electrorotation test platform. Background technique [0002] Electrorotation (ROT) technology is a new technology for studying the characteristics of organisms (such as cells). The principle is that when a solution containing cells or organisms is placed in a specific rotating electric field, the cells will respond differently to the rotation due to their different dielectric properties, so the cells will carry various characteristics in the rotating electric field. Regular rotation of information. Physical information corresponding to the biochemical characteristics of the subject can be extracted by measuring the size of the rotating body, the unit rotating speed, tracking the trajectory of the rotating body, and the law of individual combinat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N15/14
Inventor 杨其华刘钢海
Owner CHINA JILIANG UNIV
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