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Vinegar-processed tripterygium processing method

A technology of making tripterygium wilfordii and vinegar, which is applied in the direction of medical formula, medical preparations containing active ingredients, plant raw materials, etc., and can solve the problems of liver and reproductive system toxic side effects, lack of toxic side effects of tripterygium wilfordii, unrecorded tripterygium wilfordii decoction pieces, etc. , to achieve the effect of reducing liver and kidney toxicity, meeting clinical needs, and being easy to operate

Active Publication Date: 2015-03-18
ZHEJIANG CHINESE MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Due to its definite clinical curative effect, Tripterygium wilfordii is currently one of the most commonly used traditional Chinese medicines for the treatment of autoimmune diseases such as rheumatoid arthritis and lupus erythematosus. Therefore, "Chinese Pharmacopoeia" has not included Tripterygium wilfordii decoction pieces so far
At present, there is a lack of processing methods that can effectively reduce the side effects of tripterygium wilfordii. Therefore, it is of great significance to study a processing method with clear composition changes, significant immune activity, and low liver and kidney toxicity for the clinical application of tripterygium wilfordii.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Take 100 g of Tripterygium wilfordii medicinal materials after removing the root bark and other non-medicinal parts, slice them, put them in a tray, take 10 g of rice vinegar as an excipient, add them to the medicinal materials of Tripterygium wilfordii, mix well, cover with a mulch, simmer for 4 hours, take them out and place them in In the cage, after steaming for 1 hour, take it out, put it in an 80°C hot air circulation oven to dry for 4 hours, take it out and let it cool, seal and package it.

Embodiment 2

[0023] Take 100 g of Tripterygium wilfordii medicinal materials after removing the root bark and other non-medicinal parts, slice them, put them in a tray, take 20 g of rice vinegar as an auxiliary ingredient, add them into the medicinal materials of Tripterygium wilfordii, mix well, cover with a mulch, moisten for 4 hours, take them out and place them in In the cage, after steaming for 2 hours, take it out, put it in a 60°C hot air circulation oven to dry for 8 hours, take it out and let it cool, then seal and package it.

Embodiment 3

[0025] Take 100 g of Tripterygium wilfordii medicinal materials after removing the root bark and other non-medicinal parts, slice them, take 30 g of rice vinegar as an excipient, add them into the medicinal materials of Tripterygium wilfordii, mix well, put them in a tray, cover them with mulch, simmer for 4 hours, take them out, put them in In the cage, after steaming for 4 hours, take it out, put it in a 90°C hot air circulation oven to dry for 3 hours, take it out and let it cool, seal and pack it, and that's it.

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PUM

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Abstract

The invention provides a vinegar-processed tripterygium processing method. The vinegar-processed tripterygium processing method comprises the following steps of: (1) taking a tripterygium root, removing a non-medicinal part, slicing, adding 10-40% of rice vinegar counted by the mass of the tripterygium, storing the tripterygium into a proper container, and soaking the tripterygium for 4-24 hours in a sealed way; (2) storing the tripterygium in a proper container, steaming the tripterygium on water for 1-6 hours; and (3) putting the steamed tripterygium into proper drying equipment, and drying the tripterygium for 1-9 hours at 50-150 DEG C till the moisture content of the tripterygium is 5-15%, and taking out and cooling the tripterygium to obtain the vinegar-processed tripterygium. The vinegar-processed tripterygium processing method is simple and easy to operate, is applicable to mass production, and can effectively meet clinical needs; in-vitro cell experiments prove that the obtained vinegar-processed tripterygium (decoction tablet) can not only keep significant immunosuppressive activity of the tripterygium, but also reduce liver and kidney toxicity caused by the tripterygium.

Description

(1) Technical field [0001] The invention relates to a preparation method of Tripterygium Vinegar. (2) Background technology [0002] Tripterygium wilfordii is the root of Triptergium wilfordii Hook. F, also known as heartbroken grass and yellow vine root. It has the effects of dispelling wind and dampness, promoting blood circulation and dredging collaterals, reducing swelling and pain, killing insects and detoxifying. Clinical application first appeared in "Wang Lian Shi Fang" in "Compendium of Materia Medica", mainly used as pesticides and treatment of rheumatoid arthritis and other diseases. [0003] Tripterygium wilfordii is one of the most commonly used traditional Chinese medicines for the treatment of autoimmune diseases such as rheumatoid arthritis and lupus erythematosus due to its definite clinical efficacy. Therefore, "Chinese Pharmacopoeia" has not included Tripterygium wilfordii pieces so far. At present, there is no processing method that can effectively red...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/37A61P37/06A61P19/02A61P29/00A61P19/04A61P33/00A61K125/00
Inventor 范永升沈炜石森林寿旗扬屠珏魏颖慧吴佳
Owner ZHEJIANG CHINESE MEDICAL UNIVERSITY
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