Reconstruction method and imaging device of three-dimensional profiles of object surfaces

Abstract

The invention relates to a reconstruction method and an imaging device of three-dimensional profiles of object surfaces. The reconstruction method includes that a reference plane plate is placed on a rotary table, light emitted by a luminous diode is projected to the surface of the reference plane plate to form a plurality of stripes through gratings, and a camera shoots the stripes of the reference plane plate and sends the stripes to a computer; an object to be tested is placed on the rotary table, the light emitted by the luminous diode is projected to the surface of the reference plane plate to form the plurality of the stripes through gratings, the camera shoots the stripes of the reference plane plate and sends the stripes to the computer; a controller controls the rotary table to rotate, and the camera shoots n frames of stripe images of the object to be tested in a range of 360 degrees; the computer obtains partial profiles of the surface of the object to be tested at n different angles through a single frame Fourier transform profilometry method; and a complete profile of the object to be tested is obtained by synthesizing the partial profiles of the surface of the object to be tested at all angles. The reconstruction method and the imaging device of three-dimensional profiles of object surfaces can be widely applied to three-dimensional profile reconstruction of object surfaces of fluorescence molecular tomography.

Description

technical field [0001] The invention relates to an object surface reconstruction method and an imaging device, in particular to an object surface three-dimensional contour reconstruction method and an imaging device suitable for fluorescent molecular tomography imaging. Background technique [0002] Fluorescence molecular tomography has become an important method for life medical research, which is helpful for early disease diagnosis, especially cancer diagnosis and localization, and effectively promotes the development of drugs and the analysis of life mechanisms. Fluorescence molecular tomography methods can be mainly divided into finite element-based methods and radiation transfer equation-based methods. Regardless of the reconstruction method, it is necessary to predict the boundary fluorescence data in the forward problem, and then update it in the inversion problem. Optical parameter values ​​for the model to minimize the difference between boundary measurements and fo...

AI Technical Summary

Problems solved by technology

[0003] At present, the existing technology solves the problem of object surface contour reconstruction in fluorescence molecular tomography, such as the back projection reconstruction method under white light, which has the advantage that it can basically achieve the contour accuracy required by the fluorescence molecular tomography method, but the imaging accuracy is not high. The light source still interferes with the fluorescence band to a certain extent, and data acquisition takes up CCD resources; the contour extraction method based on Gray-coded structured light has the advantage of achieving high resolution through calibration, but for objects at the same angle, reconstruction requires much Frame Gray coded images is very time-consuming, and the device for switching patterns will greatly increase the complexity and cost of the system, so the effect is not ideal

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