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Plastics for promoting healing of skin wound and preparation method of plastics

A technology for skin wounds and film-coating agents, which is applied in the direction of skin diseases, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem of lack of film-coating agents for skin wound healing, and promote wound healing Repair and healing, broad application prospects, remarkable curative effect

Inactive Publication Date: 2014-11-19
CHONGQING ACADEMY OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the coating agents used to promote wound healing have their own advantages, but there are also deficiencies in varying degrees. There is a lack of a satisfactory coating agent that can promote skin wound healing

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1 is used for the preparation method of the coating agent that promotes skin wound healing

[0024] (1) Get 50g of the medicinal composition, which consists of 2 to 3 parts of Angelica sinensis, 2 to 3 parts of Panax notoginseng, 2 to 3 parts of Scutellaria baicalensis, 2 to 3 parts of Cortex Phellodendri, 1 to 2 parts of frankincense, 1~2 parts of myrrh, 1~2 parts of red peony root, 1~2 parts of forsythia, 1~2 parts of rhubarb, 1~2 parts of honeysuckle, 1~2 parts of comfrey and 1~2 parts of licorice, with 510ml 60 % ethanol was heated to reflux at 85°C for 2 hours, filtered, the filtrate was concentrated to 40ml, and then 60ml of absolute ethanol was added to dilute to 100ml to obtain a traditional Chinese medicine solution;

[0025] (2) Take 6g of polyvinyl alcohol 1788, add 30ml of water, heat in a water bath at 70°C to dissolve completely, and obtain solution I, which is transparent;

[0026] (3) Take 1g of Bletilla striata and reflux it with 10ml of wat...

Embodiment 2

[0033] Embodiment 2 is used to promote the effectiveness experiment of the coating agent of skin wound healing

[0034] There are 7 patients who voluntarily participated in the effectiveness test of film-coating agent of the present invention. The patient smears the coating agent prepared in Example 1 on the affected part of the skin once a day, and 7 days is a course of treatment. Observe the patient's wound hemostasis, inhibition of inflammation, anti-exudation and wound healing effects. Test results show that the film coating agent of the present invention can effectively antibacterial and anti-inflammatory, promote blood circulation and remove blood stasis, resist exudation, and promote wound repair and healing. The total effective rate is 100%, and the 7-day complete cure rate is 70%.

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Abstract

The invention discloses plastics for promoting the healing of skin wound and a preparation method of the plastics. The plastics comprises a traditional Chinese medicine solution and auxiliary materials, wherein the traditional Chinese medicine solution is derived from an alcohol extraction solution of a medicine composition, the pharmaceutical composition comprises Chinese angelica, radix notoginseng, baical skullcap root, phellodendron amurense, boswellia carterii, myrrh, common peony root, fructus forsythiae, radix et rhizoma rhei, honeysuckle flower, sinkiang arnebia root and liquorice; and the excipients comprise polyvinyl alcohol 1788, bletilla striata gelatin, chitosan, glycerol, polyethylene glycol 400, azone, eucalyptol, absolute ethyl alcohol, water, glacial acetic acid and borneol, and the volume of the traditional Chinese medicine solution to the auxiliary materials is 1:(4-5). The invention also provides a preparation method of the plastics for promoting skin wound healing. The plastics has the functions of effectively resisting bacteria and diminishing inflammation, invigorating the circulation of blood, removing blood stasis, resisting exudation and promoting the wound repairing and healing, and provides a new convenient, effective and safe path for promoting the healing of the wound.

Description

technical field [0001] The invention belongs to the technical field of biology, medicine and medical equipment. Specifically, the present invention relates to an external Chinese medicine for promoting skin wound healing, in particular to a coating agent for promoting skin wound healing and a preparation method thereof. Background technique [0002] In daily life, due to careless work, people often have skin trauma and damage, local wounds will have different degrees of tissue necrosis and blood vessel rupture and bleeding, and inflammatory reactions will occur, causing local redness and swelling. Therefore, promoting wound healing has become an important research topic in the field of wound repair. With the extensive long-term experimental research from human tissue to cell, molecular and gene levels in the domestic and foreign medical circles, the content of promoting wound repair has been greatly improved, and it has played a significant role in promoting wound healing. ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/756A61K9/08A61K47/46A61P17/02
Inventor 李滨秦建波
Owner CHONGQING ACADEMY OF SCI & TECH
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