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Pharmaceutical composition for treating phlebitis

A composition and phlebitis technology, which are applied in directions such as drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve problems such as unsatisfactory effects, and achieve the effects of simple and feasible preparation method, fast film-forming speed and low cost.

Inactive Publication Date: 2013-02-27
CHONGQING ACADEMY OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine often uses 50% magnesium sulfate or Hirudoid ointment for external application in the treatment of phlebitis, but the effect is not satisfactory

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1 The pharmaceutical composition for the treatment of phlebitis

[0021] It consists of the following components according to the ratio of parts by weight: 2~3 parts of angelica, 2~3 parts of Panax notoginseng, 1~2 parts of Scutellaria baicalensis, 1~2 parts of frankincense, 1~2 parts of myrrh, 1~2 parts of gardenia, 1~2 parts of safflower, 1~2 parts of rhubarb, 1~2 parts of Smilax smilax and 1~2 parts of licorice.

Embodiment 2

[0022] Example 2 The preparation method of the coating agent prepared from the ethanol extract of the pharmaceutical composition for treating phlebitis and auxiliary materials

[0023] (1) Get 34g of the pharmaceutical composition for the treatment of phlebitis, the pharmaceutical composition consists of 2 to 3 parts of Angelica sinensis, 2 to 3 parts of Panax notoginseng, 1 to 2 parts of Scutellaria baicalensis, 1 to 2 parts of frankincense, Composed of 1~2 parts of myrrh, 1~2 parts of gardenia, 1~2 parts of safflower, 1~2 parts of rhubarb, 1~2 parts of Smilax cocos and 1~2 parts of licorice, heated to reflux with 500ml 60% ethanol at 80°C After 2 hours, the filtrate was concentrated to 50ml, and then 50ml of absolute ethanol was added to set the volume to 100ml to obtain the ethanol extract of the pharmaceutical composition;

[0024] (2) Take 1g of Carbomer 940, add 40ml of absolute ethanol, stir and dissolve to obtain solution I;

[0025] (3) Take 11g of polyvinyl alcohol ...

Embodiment 3

[0030] Example 3 Effectiveness experiment of the pharmaceutical composition for treating phlebitis and the film preparation prepared from the ethanol extract of the pharmaceutical composition for treating phlebitis and auxiliary materials

[0031] Have 5 phlebitis patients voluntarily participate in the validity test of the present invention. The patient smears the coating agent prepared in Example 2 on the affected area every day, and the film can be formed in 2-5 minutes. The skin has good adhesion and is not easy to fall off. 7 days is a course of treatment. Test results show that the total effective rate of the film coating agent of the present invention for treating phlebitis is 100%, and the complete cure rate is 80%.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating phlebitis. The pharmaceutical composition is composed of the following ingredients in parts by weight: 2-3 parts of angelica, 2-3 parts of notoginseng, 1-3 parts of radix scutellariae, 1-2 parts of frankincense, 1-2 parts of myrrh, 1-2 parts of cape jasmine, 1-2 parts of safflower, 1-2 parts of rhubarb, 1-2 parts of rhizoma smilacis glabrae and 1-2 parts of liquorice. The invention further discloses a liniment prepared from ethanol extract of the pharmaceutical composition and common medical additives and a preparation method of the liniment. The liniment is fast in film forming speed, good in skin adhesiveness, difficult to drop, capable of effectively treating phlebitis and high in cure rate.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, specifically relates to a pharmaceutical composition for treating phlebitis, and further relates to a coating agent prepared from the ethanol extract of the pharmaceutical composition for treating phlebitis and auxiliary materials and a preparation method thereof. Background technique [0002] Phlebitis caused by intravenous infusion is a common clinical complication of infusion therapy. According to reports, the incidence of phlebitis is 30% to 70%, and about 50% to 80% of chemotherapy patients have different degrees of phlebitis. Western medicine often uses 50% magnesium sulfate or Hirudoid ointment for external application in the treatment of phlebitis, but the effect is not satisfactory. Therefore, traditional Chinese medicine therapy has attracted the attention of medical experts. Traditional Chinese medicine believes that phlebitis is caused by multiple reasons such a...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61P9/00
Inventor 李滨秦建波
Owner CHONGQING ACADEMY OF SCI & TECH
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