Preparation method of natural borneol

Abstract

The invention discloses a preparation method of natural borneol and relates to the field of traditional Chinese medicine preparation methods. The preparation method comprises the following steps of distillation, dissolution absorption adopting a solvent, refrigeration crystallization, centrifugal separation, natural borneol crude product collection and purification, wherein the dissolution absorption adopting a solvent comprises dissolving essential oil carried by steam distilled from cinnamonum camphora (L.) presley branches and leaves in the solvent, and continually diluting the solvent so that natural borneol is separated out. The preparation method has the advantages that 1, through a solvent-based dissolution method, a distillate of essential oil of cinnamonum camphora (L.) presley branches and leaves is directly dissolved in a solvent so that it is avoided that borneol in distillate produced by the traditional preparation method condenses on a condenser in distillate condensation thereby causing pipe blocking; condenser dredge and cleaning processes are saved; operation time is reduced; and a product loss is reduced; and 2, through utilization of ethanol having a concentration of 40 to 95% as an absorption dissolution solvent, a separation effect is improved.

Description

technical field [0001] The invention relates to a preparation method in the field of traditional Chinese medicine, in particular to a preparation method of natural borneol. Background technique [0002] Natural borneol is made by extracting and processing the fresh branches and leaves of Cinnamonum Camphora (L.) presley, which is a white crystalline powder or flaky crystal. Fragrant, pungent, cool, volatile, thick smoke when ignited, yellow flame, melting point 204-209°C, specific rotation +34°-+39°, easily dissolved in ethanol, trichloro, methanol or ether Soluble, almost insoluble in water. Natural borneol has the effects of resuscitating the mind, clearing away heat and relieving pain. It is used for febrile coma, convulsions, apoplexy and phlegm, qi stagnation violent, middle-evil coma, chest pain and heartache, red eyes, sore throat, ear canal discharge, etc. . At present, the method of extracting and preparing natural borneol in China is: steam distillation of borne...

AI Technical Summary

Problems solved by technology

At present, the method of extracting and preparing natural borneol in China is: steam distillation of borneol camphor leaves→condensation and collection of distillate→oil-water separation→freezing→centrifugal separation→crude natural borneol→refining, using this method to prepare natural borneol and receive distillate When the temperature rises, the solvent and borneol are lost. At the same time, there are also problems such as easy blockage of the condensation pipe, high-quality borneol with many impurities, and repeated refining.