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Traditional Chinese medicine composition for treating sjogren syndrome as well as preparation method and application thereof

A technology for Sjögren's syndrome and composition, which is applied in the field of traditional Chinese medicine compositions and preparations for treating Sjögren's syndrome, can solve the problems of damage to other organs, easy generation of drug resistance, unsatisfactory curative effect, etc., and achieves strict compatibility, no toxic side effects, Well-designed effects

Inactive Publication Date: 2013-02-20
THE FIRST AFFILIATED HOSPITAL OF XINXIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the current medicine can only relieve the superficial symptoms, the curative effect is not ideal, and it is easy to relapse after stopping the medicine. disease, has become the eager expectation of the majority of patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1: Take 20g of Cornus officinalis, 30g of Chinese yam, 10g of Alisma, 25g of Polygonatum, 15g of Forsythia, 20g of Cistanche, 10g of Radix Paeoniae Alba, 20g of Radix Paeoniae Alba, 10g of Dendrobium, 25g of Danpi, 15g of Rehmannia, 25g of Poria cocos, 30g of Ophiopogon japonicus, Combine 25g of Eucommia ulmoides, 10g of Xu Changqing, and 20g of licorice, add water to decoct twice, add water to 10 times the weight of the medicinal material for the first time, decoct for 1.5h, add water for the second time to 8 times the weight of the medicinal material, and decoct for 1.5h, Combine the decoctions, concentrate under reduced pressure at 0.07MPa, 60-70°C to a relative density of 1.15 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 75% (v / v), stir, and let stand After 24 hours, the filtrate was decompressed to recover ethanol and concentrated, and the filtrate was concentrated under reduced pressure at 0.07MPa and 65°C to a relative density of 1.25 a...

Embodiment 2

[0020] Example 2: Get 25g of Cornus officinalis, 25g of Chinese yam, 15g of Alisma, 20g of Polygonatum, 20g of Forsythia, 15g of Cistanche, 15g of Radix Paeoniae Alba, 15g of Radix Paeoniae Alba, 15g of Dendrobium, 20g of Danpi, 20g of Rehmannia, 20g of Poria cocos, 40g of Ophiopogon japonicus, Combine 20g of Eucommia ulmoides, 15g of Xu Changqing, and 15g of licorice, add water to decoct twice, add water to 8 times the weight of the medicinal materials for the first time, decoct for 1 hour, add water for the second time to 6 times the weight of the medicinal materials, decoct for 1 hour, and combine Decoction, 0.07MPa, concentrated under reduced pressure at 60-70°C until the relative density is 1.10 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 65% (v / v), stir, stand still, Filter, add water and auxiliary materials to prepare oral liquid.

Embodiment 3

[0021] Example 3: Get 30g of Cornus officinalis, 20g of Chinese yam, 20g of Alisma, 15g of Polygonatum, 25g of Forsythia, 10g of Cistanche, 20g of Radix Paeoniae Alba, 10g of Radix Paeoniae Alba, 20g of Dendrobium, 15g of Cortex Paeonol, 25g of Rehmannia, 15g of Poria cocos, 50g of Ophiopogon japonicus, Combine 15g of Eucommia ulmoides, 20g of Xu Changqing, and 10g of licorice, add water to decoct twice, add water to 12 times the weight of the medicinal materials for the first time, decoct for 2 hours, add water for the second time to 10 times the weight of the medicinal materials, decoct for 2 hours, and combine Decoction, 0.07MPa, concentrated under reduced pressure at 60-70°C to a relative density of 1.20 at 65°C, add 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stir, and stand for 24 Hours, the filtrate was decompressed to recover ethanol and concentrated, and the filtrate was concentrated under reduced pressure at 0.07MPa and 65°C to a relative density of...

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Abstract

The invention provides a traditional Chinese medicine composition for treating sjogren syndrome. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20 to 30 parts of dogwood, 20 to 30 parts of rhizoma dioscoreae, 10 to 20 parts of rhizoma alismatis, 15 to 25 parts of rhizoma polygonati, 15 to 25 parts of fructus forsythiae, 10 to 20 parts of cistanche deserticola, 10 to 20 parts of radix paeoniae rubra, 10 to 20 parts of radix paeoniae alba, 10 to 20 parts of dendrobium nobile, 15 to 25 parts of cortex moutan, 15 to 25 parts of radix rehmanniae, 15 to 25 parts of poria cocos, 30 to 50 parts of radix ophiopogonis, 15 to 25 parts of eucommia ulmoides, 10 to 20 parts of cynanchum paniculatum, and 10 to 20 parts of liquorice. The traditional Chinese medicine composition has the effects of moistening lung and promoting secretion, so that the purpose of treating sjogren syndrome can be achieved. The invention also discloses a preparation method and application of the traditional Chinese medicine composition.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating Sjögren's syndrome, a preparation method and application. Background technique [0002] Sjögren's syndrome has a high incidence rate, mostly in women over 40 years old. The pathological mechanism is mainly due to the excessive autoimmune response, resulting in the infiltration of a large number of lymphocytes and plasma cells in the exocrine glands, causing the destruction of glandular cells and loss of function, resulting in a series of clinical symptoms and manifestations. Traditional Chinese medicine believes that there are two causes of Sjogren's syndrome: external dryness and internal dryness, with internal dryness being the most common. The pathogenicity of dryness is most seasonal. After the autumnal equinox, dry metal is the main thing. People steam through the summer moon, and the liquid is swe...

Claims

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Application Information

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IPC IPC(8): A61K36/8984A61P37/02
Inventor 不公告发明人
Owner THE FIRST AFFILIATED HOSPITAL OF XINXIANG MEDICAL UNIV
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