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Medicinal composition and application thereof

A composition and drug technology, applied in the field of medicine, can solve the problem of less compatibility of traditional Chinese medicine monomers

Active Publication Date: 2013-02-06
SHANGHAI INST OF MATERIA MEDICA CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, many formulas for the treatment of myocardial ischemia have been developed in China, but there are still relatively few studies on myocardial protection drugs in myocardial ischemia-reperfusion, and there are even fewer studies on the compatibility of traditional Chinese medicine monomers; monomer compounds salvianolic acid B and Compatibility of ginsenoside Rg1 in the treatment of myocardial ischemia reperfusion, no similar research and development reports in China

Method used

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  • Medicinal composition and application thereof
  • Medicinal composition and application thereof
  • Medicinal composition and application thereof

Examples

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Embodiment 1

[0016] Take 1:5 as an example to illustrate the drug configuration method: Weigh 0.83mg salvianolic acid B and 4.17mg ginsenoside Rg1, mix them evenly (the total amount is 5mg), dissolve them in 0.5ml filtered normal saline, and vortex for 3 minutes Until the mixture is completely dissolved, the 1:5 pharmaceutical composition of the present invention is obtained.

[0017] According to the above method, the pharmaceutical compositions with weight ratios of 2:5, 3:5, 4:5 and 5:5 were prepared respectively.

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Abstract

The invention discloses a medicinal composition, which is mainly prepared from compound salvianolic acid B and ginsenoside Rg1 according to a certain weight part ratio. The medicinal composition has a protection effect on cardiac muscle in myocardial ischemia and reperfusion and can be used for treating cardiovascular diseases.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a pharmaceutical composition and its use in the preparation of medicines for treating cardiovascular diseases. Background technique [0002] Myocardial ischemia is one of the common cardiovascular diseases among middle-aged and elderly people. It refers to myocardial dysfunction or organic disease caused by coronary artery stenosis and insufficient blood supply. Thrombolytic therapy and intervention in the acute stage of myocardial infarction are the guarantee It is a very important means of patient prognosis. Thrombolysis is often accompanied by the risk of myocardial ischemia-reperfusion. The invention studies the cardioprotective effect of the combination of salvianolic acid B and ginsenoside Rg1 in myocardial ischemia-reperfusion. At present, many formulas for the treatment of myocardial ischemia have been developed in China, but there are still relatively few studies on myocardial p...

Claims

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Application Information

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IPC IPC(8): A61K31/704A61K31/343A61P9/00A61P9/10A61P9/04
Inventor 果德安姜宝红邓燕萍
Owner SHANGHAI INST OF MATERIA MEDICA CHINESE ACAD OF SCI
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