Chinese medicinal composition for raising leucocytes and preparation method and application thereof
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A technology for raising leukocytes and a preparation process, which is applied in the field of traditional Chinese medicine compositions for raising leukocytes, and can solve the problems of limited curative effect and inability to effectively repair bone marrow hematopoietic microcirculation.
Active Publication Date: 2015-07-15
LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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Problems solved by technology
[0007] The technical problem to be solved by the present invention is to overcome the defects that the existing western medicines for raising leukocytes cannot effectively repair the repeatedly damaged bone marrow hematopoietic microcirculation, and traditional Chinese medicines have limited curative effect on severe myelosuppression, and provide a kind of medicine that can raise white blood cells. , a traditional Chinese medicine composition for effectively promoting the recovery of hematopoietic function and its preparation process and application
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Embodiment 1
[0053] Example 1 Preparation of oral liquid formulation
[0054] 1. Weigh the raw Chinese medicinal materials: Astragalus 30Kg, Polygonatum 30Kg.
[0055] 2. Decoct the above medicinal materials with 15 times the mass of water for 3 hours, filter, add water to the filter residue and decoct repeatedly, filter, combine the two filtrates, centrifuge to remove solid matter, take the supernatant and concentrate to obtain a clear Paste (relative density 0.8, temperature 59°C).
[0056] 3. Add 1kg sweetener, 2kg potassium sorbate, stir and add 30L water, 10wt% NaOH aqueous solution to adjust the pH to 6-7, filter, fill, and sterilize.
Embodiment 2
[0057] Example 2 Preparation of granules
[0058] Weigh 30Kg of Astragalus polysaccharide extract, 30Kg of Polygonatum polysaccharide extract, 0.3Kg of total Astragalus flavonoids extract, 1Kg of Astragalus saponins extract, 1.5Kg of Polygonatum saponins extract, and add equal mass of dextrin and 5wt% of granules The sweetener is dried, granulated and whole.
Embodiment 3
[0059] Example 3 Preparation of capsule formulation
[0060] Mix 30Kg of astragalus polysaccharide extract, 1Kg of astragalus saponins extract, 10Kg of Polygonatum polysaccharide extract, and 0.5Kg of total saponins extract of Polygonatum, then mix with starch, granulate, sieving, drying, whole and filling, ready to get Capsules.
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Abstract
The invention discloses a Chinese medicinal composition for raising leucocytes, which is mainly prepared from the following raw material medicaments of Radix Astragali and polygonatum rhizome according to weight ratio being 1:1-2:1. The invention discloses a traditional Chinese medicine for raising leucocytes, the active components are a Radix Astragali extract product and a polygonatum rhizome extract product, wherein the Radix Astragali extract product is at least a Radix Astragali polysaccharide extract product, and the polygonatum rhizome extract product is at least a polygonatum rhizome polysaccharide extract product; and the weight ratio of the Radix Astragali polysaccharide extract product to the polygonatum rhizome polysaccharide extract product is 1:1-3:1. The invention also discloses a preparation method and an application of the Chinese medicinal composition for raising leucocytes. The Chinese medicinal composition for raising leucocytes promote the differentiation propagation of the leucocytes and bone marrow cells, raising the leucocytes of the chemicotherapy patients, preventing and controlling marrow suppression of chemoradiotherapy, and improving Chinese medicinal symptoms and living quality of patients with cancer; for the patients with qi deficiency, through supplementing qi and nourishing Yin, the immunity is enhanced for improving the recovery of the patients with qi deficiency, and no toxic and side effects can be generated.
Description
Technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for raising white blood cells, and a preparation process and application thereof. Background technique [0002] At present, surgery, radiotherapy, and chemotherapy are still the main methods for the treatment of malignant tumors. Surgery is the first method of radical treatment of tumors. For some limited tumors, surgery alone can sometimes be cured, but many patients cannot prevent tumor recurrence and distant metastasis by surgery alone. If surgery is combined with radiation or chemotherapy treatment, For many tumors, even palliative surgery can achieve better results. Although radiotherapy can cure a variety of tumors, it has certain limitations. Chemotherapy has a short history of development. Currently, it is used alone in most tumors at the level of palliative treatment, but for some tumors, a very high cure rate has been a...
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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8969A61P7/00A61P37/04
Inventor 徐振晔王立芳吴秋霞蔡晓月顾贤王爽
Owner LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE