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A Chinese medicinal effective fraction composition for treating depression

A technology of effective parts and compositions, applied in the field of medicine, to achieve the effect of significant curative effect

Active Publication Date: 2013-01-02
王宇红 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no traditional Chinese medicine with effective parts of the antidepressant compound formula, and the antidepressant effects of Hypericum perforatum total flavonoids, total ginsenosides, and curcumin, which use the effective parts as the main active ingredients, have different emphases and differences, and there is a huge demand for combined drugs in clinical practice

Method used

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  • A Chinese medicinal effective fraction composition for treating depression
  • A Chinese medicinal effective fraction composition for treating depression
  • A Chinese medicinal effective fraction composition for treating depression

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Granule, tablet or capsule dosage form of embodiment 1 pharmaceutical composition of the present invention

[0035]Preparation of granules: adopt conventional granule preparation process, take 0.5 part of total flavonoids of Hypericum perforatum, 1 part of total ginsenosides, 0.5 part of curcumin, and appropriate amount of auxiliary materials. Mixing, granulating, sieving, and drying to obtain a pharmaceutical composition in the form of granules.

[0036] Preparation of tablet: the obtained granules are further pressed into tablets and dried to obtain a pharmaceutical composition in tablet form containing 0.5 part of total flavonoids of Hypericum perforatum, 1 part of total ginsenosides and 0.5 part of curcumin.

[0037] Capsule preparation: put the prepared granules into capsule shells to make capsules, namely to prepare a pharmaceutical composition in capsule form containing 0.5 part of total flavonoids of Hypericum perforatum, 1 part of total ginsenosides and 0.5 par...

Embodiment 2

[0038] The drop pill dosage form of embodiment 2 compositions of the present invention

[0039] Preparation: adopt the conventional technique for preparing dropping pills, take 1 part of total flavonoids of Hypericum perforatum, 0.5 part of total ginsenosides, 1 part of curcumin, and appropriate amount of auxiliary materials to prepare the dropping pills of the pharmaceutical composition.

Embodiment 3

[0040] The soft capsule dosage form of embodiment 3 compositions of the present invention

[0041] Preparation: adopt conventional soft capsule preparation technology, take 1.5 parts of total flavonoids of Hypericum perforatum, 1 part of total ginsenosides, 2 parts of curcumin, appropriate amount of auxiliary materials, mix well, use gelatin as capsule shell material, press into soft capsules, and obtain the Soft capsules of pharmaceutical composition.

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Abstract

The invention discloses a Chinese medicinal effective fraction composition for treating depression, comprising Hypericum perforatum extract containing Hypericum perforatum total flavonoids as effective fraction, Curcuma longa extract containing curcumin as effective fraction, and Panax ginseng extract containing ginsenoside as effective fraction. The invention can utilize the compatibility of the ingredients to treat depression, take multi-link, multi-path, multi-target action in soothing the liver, relieving the depressed liver, and relieving mental stress. The composition may be in the medically acceptable solid oral preparation in dosage form of such as tablet, capsule (soft capsule or hard capsule) and granule. Pharmacological research on effective fractions extracted from the formulation shows that the medicine has specific inhibitory effect on multiple depression models.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a medicine for treating depression, in particular to a traditional Chinese medicine effective part composition composed of total flavonoids of Hypericum perforatum, total ginsenosides and curcumin. Background technique [0002] Depression is a common emotional and mental disorder. With the acceleration of the pace of social life, depression has become a high-risk disease in today's society. According to the statistics of the World Health Organization in 2005, the prevalence of various depressions accounts for about 11% of the global population. According to the epidemiological survey in my country in 2003, there are at least 36 million depression patients in my country, of which only 5% of severe patients receive relevant treatment. Many patients with major depressive disorder commit suicide due to lack of regular treatment in time. According to the analysis of death data in 200...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K36/258A61P25/24A61K31/12
Inventor 王宇红韩远山
Owner 王宇红
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