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A cell tracking statistical analysis system and method

A statistical analysis and cell technology, applied in the field of cell tracking statistical analysis system, can solve the problems of unfavorable data processing, low efficiency, time-consuming and laborious, etc.

Active Publication Date: 2016-03-23
HUAZHONG UNIV OF SCI & TECH
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Problems solved by technology

[0007] Therefore, the existing method requires a lot of manual operations, which is time-consuming, laborious, and inefficient. At the same time, it lacks the connection interface with common statistical analysis software, which is not conducive to the further processing of data.

Method used

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  • A cell tracking statistical analysis system and method
  • A cell tracking statistical analysis system and method
  • A cell tracking statistical analysis system and method

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Embodiment Construction

[0064] Data Sources:

[0065] Target tracking software is used to perform target tracking analysis on the time series images, usually microscopic optical imaging images containing four-dimensional information (x, y, z, t) of cell movement, to obtain the original data of the cell tracking results of each sample.

[0066] see figure 1 , an embodiment of the present invention provides a cell tracking statistical analysis system, including a parameter setting module, a multi-sample comparison analysis module based on secondary parameters, an origin normalized trajectory analysis module, and a trajectory tracking analysis module; wherein, the parameter setting modules are respectively It is connected with the multi-sample comparative analysis module based on the secondary parameters, the origin normalized trajectory analysis module and the trajectory tracking analysis module through the data interface;

[0067] The parameter setting module sets various parameters of the sample acc...

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Abstract

The invention discloses a cell tracking statistical analysis system and a cell tracking statistical analysis method, and belongs to the field of data processing and image processing. The system comprises a parameter setting module, a secondary parameter-based multi-sample comparative analysis module, an origin normalized trajectory analysis module, and a trajectory tracking analysis module, wherein the parameter setting module is connected with the secondary parameter-based multi-sample comparative analysis module, the origin normalized trajectory analysis module and the trajectory tracking analysis module through data interfaces. According to the system and the method, the data acquired by target tracking software are subjected to effective, quick and flexible postprocessing in batches aiming at one or more selected samples, so that parameters which can describe cell movement characteristics intuitively are acquired, and related parameter curves and different types of cell movement trajectory are drawn for observing and comparing the difference of the cell movement characteristics of different samples.

Description

technical field [0001] The invention belongs to the field of data processing and image processing, in particular to a cell tracking statistical analysis system and method. Background technique [0002] Based on optical microscopic imaging technology, the study of cell movement and the interaction between cells in the living body, and then the process and mechanism of various reactions in the living body are of great significance to the basic research of life sciences and the research of various human diseases. However, the data usually obtained are four-dimensional information (x, y, z, t) of cell morphology and motion properties, and the data volume can usually reach several gigabytes. The visualization and analysis of this data is a major challenge. [0003] Software with cell tracking functions include ImageJ plug-ins (such as ParticleTracker, SpotTracker, etc.), Image-ProPlus, Volocity, etc. Among them, Image-ProPlus can not only obtain the coordinates of the cell move...

Claims

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Application Information

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IPC IPC(8): G06F19/24G06F19/26G16B45/00
Inventor 李慧付玲崔权张智红骆清铭
Owner HUAZHONG UNIV OF SCI & TECH
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