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Traditional Chinese medicine composition and preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and its preparation, can solve the problem that the therapeutic effect of Hypericum perforatum extract has not reached the ideal level, and achieve the effect of no drug dependence, no toxic and side effects, and good curative effect

Inactive Publication Date: 2012-11-14
INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Existing research data show that some fat-soluble ingredients and highly polar or water-soluble plant ingredients in traditional Chinese medicine have significant antidepressant activity, suggesting that traditional Chinese medicine that works through multiple channels, multiple targets, and multiple levels should be considered in the treatment of depression. In recent years, it has also been found that traditional Chinese medicine (such as Hypericum perforatum) can treat depression, but the therapeutic effect of Hypericum perforatum extract has not reached the ideal level, and there is still room for improvement in the efficacy of using traditional Chinese medicine to treat depression

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1: prepare the capsule of Chinese medicine composition of the present invention

[0032] Weigh each raw material according to the following weight (unit: g): 300 curculigo, 100 betel nut, 300 spider incense, 200 ganoderma lucidum, 200 morinda officinalis, 200 acacia juniper, 300 licorice;

[0033] Curculigo, betel nut, spider incense, Ganoderma lucidum, Morinda officinalis, Albizia Julibrissin and licorice are decocted twice with water 6 times the total weight of the raw material medicine, decocting for 1 hour each time, filtering, and combining the filtrates filtered each time, the filtrate Concentrate to a relative density of about 1.10-1.15 (56°C) to obtain a concentrated solution, add ethanol to the concentrated solution to adjust the alcohol concentration (volume percentage) to 80%, refrigerate (0-10°C) for 24 hours, filter, and filtrate After recovering ethanol under reduced pressure, dry under reduced pressure at a pressure of 0.06-0.08Mpa and a temper...

Embodiment 2

[0034] Embodiment 2: prepare the tablet of Chinese medicine composition of the present invention

[0035] Weigh each raw material according to the following weight (unit: g): 200 curculigo, 200 betel nut, 200 spider incense, 100 Ganoderma lucidum, 300 Morinda officinalis, 100 acacia juniper, 200 licorice;

[0036] Curculigo, betel nut, spider incense, Ganoderma lucidum, Morinda officinalis, Albizia Julibrissin and licorice are decocted 3 times with water 3 times the total weight of the raw material medicine, decocting for 3 hours each time, filtering, and combining the filtrates filtered each time, the filtrate Concentrate to a relative density of about 1.10-1.15 (56°C) to obtain a concentrated solution, add ethanol to the concentrated solution to adjust the alcohol concentration (volume percentage) to 50%, refrigerate (0-10°C) for 24 hours, filter, and filtrate After recovering ethanol under reduced pressure, dry under reduced pressure at a pressure of 0.06-0.08Mpa and a temp...

Embodiment 3

[0037] Embodiment 3: prepare the granule of Chinese medicine composition of the present invention

[0038] Weigh each raw material according to the following weight (unit: g): 500 curculigo, 400 betel nut, 500 spider incense, 400 Ganoderma lucidum, 500 Morinda officinalis, 400 acacia juniper, 500 licorice;

[0039]Curculigo, betel nut, spider incense, Ganoderma lucidum, Morinda officinalis, Albizia Julibrissin and licorice are decocted 4 times with water 5 times the total weight of the raw material medicine, decocting for 2 hours each time, filtering, and combining the filtrates filtered each time, the filtrate Concentrate to a relative density of about 1.10-1.15 (56°C) to obtain a concentrated solution, add ethanol to the concentrated solution to adjust the alcohol concentration (volume percentage) to 90%, refrigerate (0-10°C) for 24 hours, filter, and filtrate After recovering ethanol under reduced pressure, dry under reduced pressure at a pressure of 0.06-0.08Mpa and a temp...

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PUM

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Abstract

The invention relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines: 2-5 parts of rhizoma curculiginis, 1-4 parts of semen arecae, 2-5 parts of valeriana jatamansi jones, 1-4 parts of lucid ganoderma, 2-5 parts of radix morindae officinalis, 1-4 parts of albizzia julibrissin and 2-5 parts of liquorice. In the invention, the formula is reasonably optimized; an efficient and safe traditional Chinese medicine composition is refined from seven natural traditional Chinese medicines and can effectively treat depression; and moreover, the traditional Chinese medicine composition prevents toxic and side effects and drug dependence of human bodies, has better animal anti-depression experiment efficacy over the existing common Chinese and Western medicines, and can be widely used for preparing an anti-depression medicine.

Description

technical field [0001] The invention relates to the field of preparing traditional Chinese medicine, in particular to a traditional Chinese medicine composition and its preparation method and application. Background technique [0002] With the gradual acceleration of the pace of life in modern society and increasingly fierce competition, the number of patients with depression is increasing day by day. Depression is a high-incidence mental illness, mixed with persistent depression and cognitive impairment. The incidence of depression is as high as 10% of the world's total population. The ranking of mental disorders in the total burden of disease in my country has jumped to the first place and has become a disease. The second largest disease burden, depression is the disease with the highest suicide rate, nearly 15%. It is urgent to find new methods and ways to effectively prevent and treat depression drugs, and has become an important topic of concern to people in the industr...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61P25/24
Inventor 赵友兴马青云黄圣卓戴好富罗应王辉
Owner INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI
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