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Traditional Chinese herbal composition for treating allergic purpura as well as preparation method and application thereof

A technology for allergic purpura and composition, which is applied in the directions of drug combination, allergic diseases, pharmaceutical formula, etc., can solve the problems of partial prescription thinking and unsatisfactory curative effect, etc.

Active Publication Date: 2012-10-17
GUANGXI NANNING BAIHUI PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the treatment of allergic purpura in traditional Chinese medicine is generally aimed at different types of syndrome differentiation. not satisfactory

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Prescription: Caulis Spatholobus 800g, Eclipta 400g, Motherwort 400g, Comfrey 240g, Duckweed 240g, White fresh bark 240g, Mulberry bark 240g, Nepeta 160g.

[0056] Preparation method: Take the above eight medicinal materials, add water to extract 3 times, the amount of water added is 10, 8, and 8 times, the extraction time is 2, 1, and 1 hour, filter, combine the filtrates, and concentrate under reduced pressure to 60 ° C. The extract with a density of 1.32 to 1.35 is dried under reduced pressure, crushed into fine powder, added with appropriate amount of sodium carboxymethyl starch, microcrystalline cellulose and magnesium stearate, and pressed into tablets.

Embodiment 2

[0058] Prescription: Caulis Spatholobus 700g, Eclipta 300g, Motherwort 300g, Comfrey 200g, Duckweed Grass 200g, White Fresh Peel 200g, Mulberry Bark 200g, Nepeta 120g.

[0059] Preparation method: extracting Caulis Spatholobus Spatholobus and Radix Dictatus by heating and refluxing 3 times with 90% ethanol. Ethanol, the extract with a relative density of 1.20-1.30 when the solution is concentrated to 60°C is used for later use; the dregs are mixed with mulberry bark, nepeta, comfrey, motherwort, duckweed and eclipta, and extracted twice with water. 10 and 8 times the amount in turn, and the extraction time is 2 and 1.5 hours in turn; filter, combine the filtrates, concentrate to the extract with a relative density of 1.32 to 1.35 at 60°C, mix with the above-mentioned alcohol extraction extract, dry, and grind into fine powder, add appropriate amount of sodium carboxymethyl starch, microcrystalline cellulose and magnesium stearate, and press into tablets to obtain.

Embodiment 3

[0061] Prescription: Caulis Spatholobus 600g, Eclipta 200g, Motherwort 200g, Comfrey 200g, Duckweed Grass 200g, White Fresh Peel 200g, Mulberry Bark 200g, Nepeta 200g.

[0062] Preparation method: the above eight flavors, Caulis Spatholobus and Radix Dictica were extracted by heating and refluxing with 70% ethanol for 3 times, the amount of solvent added was 7, 7, and 5 times the amount, and the extraction time was 2, 1.5, and 1 hour; filter, Combine the filtrates, recover ethanol, concentrate the solution to an extract with a relative density of 1.31 to 1.35 at 60°C, and set aside; mix the dregs with mulberry bark, nepeta, comfrey, motherwort, duckweed and eclipta, add water to extract 2 times, the amount of water added is 10, 8 times, and the extraction time is 3, 1.5 hours; filter, combine the filtrate, concentrate to the extract with a relative density of 1.31 to 1.35 at 60°C, mix with the above-mentioned alcohol extraction extract, and dry , crushed into fine powder, gran...

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Abstract

The invention provides a traditional Chinese herbal composition for treating allergic purpura and a method for preparing the same. The traditional Chinese herbal composition is prepared from 8 active pharmaceutical ingredients of suberect spatholobus stem, eclipta alba, leonurus, lithospermum, common ducksmeat herb, cortex dictamni, mulberry bark and schizonepeta according to a certain weight ratio. The traditional Chinese herbal composition has a good curative effect on allergic purpura.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating allergic purpura, a preparation method and application thereof. Background technique [0002] Henoch-Schönlein purpura, also known as Henschler's syndrome (HSP), is a relatively common microvascular allergic hemorrhagic disease. Because the body has an allergic reaction to certain sensitizing substances, the fragility and permeability of capillaries increase. , blood extravasation, resulting in skin, mucous membranes and some organ bleeding. It may be accompanied by other allergic manifestations such as angioedema and urticaria at the same time. There are many reasons for the occurrence of allergic purpura. It is generally believed that it is related to factors such as bacterial and viral infections, parasitic infections, animal protein intake, and medication. The pathogenesis is that the specific constitution is affected by the above factors, resulting in immune Dysfunc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P37/08A61P7/04
Inventor 张加余李西秦
Owner GUANGXI NANNING BAIHUI PHARMA GRP
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