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Ruhesanjie capsule used for curing mammary hyperplasia diseases of women and preparation method thereof

A technology of capsules and breast cores, which is applied in the field of drugs for the treatment of women's mammary gland hyperplasia and its preparation, and can solve the problems of low bioavailability, difficult control of quality standards, and poor stability of drugs, etc.

Inactive Publication Date: 2012-10-10
刘坤
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, according to the causes of mammary gland hyperplasia, there are many traditional Chinese medicines on the market, such as Ruhe Sanjie Tablets, Ruhexiao Pills, Ruhe Neoxiaoye, etc. Although they have achieved certain curative effects, the drugs are stable. Poor drug resistance, low bioavailability, difficult to control quality standards, and relatively outdated dosage forms (mostly tablets, powders, liquids, etc.), some pharmaceutical preparations are also added with preservatives, which affect the safe use of preparations

Method used

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  • Ruhesanjie capsule used for curing mammary hyperplasia diseases of women and preparation method thereof
  • Ruhesanjie capsule used for curing mammary hyperplasia diseases of women and preparation method thereof
  • Ruhesanjie capsule used for curing mammary hyperplasia diseases of women and preparation method thereof

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Embodiment 1

[0055] 【prescription】

[0056] Angelica 219g, Astragalus 219g, Guangzi mushroom 219g,

[0057] Leaky reed 219g, Bupleurum 164g, turmeric 328g,

[0058] 437g of kombu, 437g of seaweed, 546g of epimedium,

[0059] 546g of deerbite grass.

[0060] 【Preparation】

[0061] 1. Grind the Angelica sinensis among the above ten medicinal materials to 40 mesh, and put it into CO 2 Extraction tank, cyclically adding CO 2 Liquid extraction, extraction temperature 40°C, extraction pressure 25MPa, extraction time 2 hours, CO 2 The flow rate is 20L / h, the pressure of the separation tank is 8MPa, and the temperature of the separation tank is 50°C. The volatile oil of Angelica sinensis is extracted, and the rest of the liquid medicine and dregs are used for standby;

[0062] 2. Dissolve gum arabic and water in a weight ratio of 1:6.7, add glycerin in a weight ratio of 1:0.017, and mix well;

[0063] 3. Add the volatile oil of Angelica sinensis to the above mixed solution, stir with an emu...

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Abstract

The invention relates to a Ruhesanjie capsule used for curing mammary hyperplasia diseases of women and a preparation method thereof. After being ground, angelica sinensis is extracted by adopting a supercritical CO2 extraction method or a steam distillation method to obtain angelica sinensis volatile oil, angelica sinensis herb liquor and angelica sinensis herb residues, and then the angelica sinensis volatile oil is manufactured into angelica sinensis volatile oil microcapsules; astragalus membranaceus, edible tulip bulbs, uniflower swisscentaury roots, bupleurum, radix curcumae, laminaria japonica, seaweed, barrenwort, pyrola and the angelica sinensis herb residues are added to water to be decocted, a filtrate obtained after the decoction is merged with the angelica sinensis herb liquor, and then the merged liquor is concentrated as thick paste; after the thick past is ground and granulated, the angelica sinensis volatile oil microcapsules and starch are added to the thick paste, and then the capsule is finally prepared. Compared with traditional drugs such as Ruhesanjie tablets, Ruhexiao pills, Ruheneixiao liquid, and the like, the Ruhesanjie capsule disclosed by the invention has the advantages of good dispersion state, short disintegration time, high drug dissolution speed, high biological availability, little toxic and side effect, and the like, is convenient to take, and achieves a good curative effect on the mammary hyperplasia diseases of the women.

Description

technical field [0001] The content of the invention belongs to the technical field of preparation of medicines, and relates to a medicine for treating hyperplasia of mammary glands in women and a preparation method thereof. Background technique [0002] Mammary gland hyperplasia belongs to the category of "breast addiction", "breast swelling" and "breast tuberculosis" in traditional Chinese medicine. It is generally divided into three types: lobular hyperplasia, fibrocystic and fibrosclerosis. It is a disease of young and middle-aged women. Common diseases and frequently-occurring diseases. The disease has the characteristics of long course of disease, complicated and changeable etiology, low clinical cure rate, and easy recurrence. In recent years, breast fibroids and other diseases caused by hyperplasia of mammary glands have been on the rise, and the probability of transforming into breast cancer is also increasing. According to related data reports, one out of every 10...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/48A61P15/14C11B9/02
Inventor 刘坤
Owner 刘坤
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