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Pharmaceutical composition and application thereof

A composition and technology for hypertension, applied in the field of medicine, can solve problems such as dose edema, and achieve the effects of reducing incidence, good compliance, and improving quality of life

Inactive Publication Date: 2014-07-02
SHIHUIDA PHARMA GRP (JILIN) LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the process of lowering blood pressure, levamlodipine can easily cause edema due to the high dose of sodium and water retention. This is the reason for a considerable number of patients to stop taking the drug, and it is clinically limited.

Method used

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  • Pharmaceutical composition and application thereof
  • Pharmaceutical composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Weigh 3 mg of levamlodipine besylate (calculated as levamlodipine) and 12000 mg of corn silk extract, and mix them uniformly to prepare pharmaceutical composition 1.

Embodiment 2

[0029] Weigh 90 mg of levamlodipine besylate (calculated as levamlodipine) and 300 mg of corn silk extract, and mix them uniformly to prepare pharmaceutical composition 2.

Embodiment 3

[0031] Weigh 7.5 mg of levamlodipine besylate (calculated as levamlodipine) and 9000 mg of corn silk extract, and mix them uniformly to prepare pharmaceutical composition 3.

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Abstract

The invention provides a pharmaceutical composition applied for preparing prevention or treatment of hypertension, which consists of levoamlodipine or medicinal salt thereof and a corn silk extract. The pharmaceutical composition is better in treatment effect on hypertension and is low in side effect.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a composition composed of levamlodipine or a pharmaceutically acceptable salt thereof and corn silk extract, and the application of the composition in the preparation of drugs for preventing or treating hypertension. technical background [0002] Hypertension is a common chronic disease of the cardiovascular system. At present, there is no effective cure in the world. Once the disease occurs, it needs to be taken for life, which seriously endangers human health. In 2009, Professor Liu Lisheng, chairman of the World Hypertension Federation, pointed out: "19% of adults in my country suffer from hypertension, and the number of patients reaches 220 million. At the same time, there are still 10 million new patients every year." Hypertension can cause damage to the heart, brain, kidney and other organs, and is closely related to sugar and lipid metabolism disorders and diabetes, which can signi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P9/12A61K31/4422
Inventor 李环杨彦玲薛传校张喜田陈明
Owner SHIHUIDA PHARMA GRP (JILIN) LTD
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