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Modeling method of jawbone osteoporosis in-vitro model and vacuum decalcification auxiliary device thereof

A technology of osteoporosis and modeling method, applied in the field of modeling of vacuum decalcification auxiliary device and jaw osteoporosis in vitro model, can solve the problems of hindering the reaction of decalcification solution, large density difference, large error, etc., to achieve Improve reproducibility, ensure bone loss, and reduce experimental error

Inactive Publication Date: 2014-12-17
FOURTH MILITARY MEDICAL UNIVERSITY
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  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] At present, studies have found that decalcification of bone can also lead to a decrease in bone density, bone strength and bone biomechanical properties
However, this method has the following disadvantages: ①The degree of osteoporosis is poorly controllable; ②The entire decalcification process is completely manual, with large errors, and it is impossible to establish a controllable and accurate mechanical model of osteoporosis; ③The cortical bone of the jaw The density of cancellous bone is quite different from that of cancellous bone. The dense cortical bone in the outer layer hinders the response of decalcification solution to the inner cancellous bone, and synchronous decalcification cannot be achieved.

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  • Modeling method of jawbone osteoporosis in-vitro model and vacuum decalcification auxiliary device thereof
  • Modeling method of jawbone osteoporosis in-vitro model and vacuum decalcification auxiliary device thereof
  • Modeling method of jawbone osteoporosis in-vitro model and vacuum decalcification auxiliary device thereof

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Embodiment Construction

[0034] Embodiments of the present invention will be described below in conjunction with the accompanying drawings, which are not intended to limit the present invention.

[0035] refer to figure 1 , figure 2 , image 3 , is a vacuum decalcification auxiliary device of the present invention, which is used for the modeling method of the osteoporotic jaw bone in vitro model. Wherein, the airtight reaction vessel 4 has a loam cake and an open glass container, and its loam cake is provided with a vacuum suction interface 8, a separatory funnel interface 2, and the vacuum suction interface 8 and the separatory funnel interface 2 are respectively provided with valves, and the vacuum suction The interface 8 is connected to the vacuum pump 6 through the vacuum suction joint 1 and the pipeline in turn, and the separatory funnel interface 2 is connected to the separatory funnel 3 . The side of the airtight reaction vessel 4 is provided with a liquid discharge port 10 and a valve for ...

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Abstract

The invention belongs to maxillofacial surgery, relates to the field of basic research of the oral implantology of alveolar surgery and the matched machinery, and discloses a modeling method of a jawbone osteoporosis in-vitro model and a vacuum decalcification auxiliary device thereof. In the modeling method of a jawbone osteoporosis in-vitro model, a vacuum reaction environment is provided by use of a vacuum decalcification auxiliary device, so that the decalcification liquid is in contact with the jawbone outer cortical bone and inner cortical bone at the same time in the largest range to ensure synchronous decalcification of the inner and outer sclerotin of a jawbone specimen; and meanwhile, by controlling the reaction time, jawbone osteoporosis in-vitro models with different bone mineral densities can be quickly and controllably established.

Description

technical field [0001] The invention belongs to maxillofacial surgery, and relates to the field of basic research on oral implantology in alveolar surgery and the field of supporting equipment, in particular to a modeling method for an in vitro model of jaw osteoporosis and a vacuum decalcification auxiliary device. Background technique [0002] Since Professor Branemark of Sweden completed the world's first dental implant restoration in 1965 and achieved good clinical results, modern oral implant technology has continued to mature, known as "the third set of teeth for humans". At present, dental implants are recognized by the stomatology community as the best permanent restoration of missing teeth. Studies have found that the key to successful implantation lies in the initial stability and long-term osseointegration of the implant. Osteoporosis and insufficient bone mass will reduce the initial stability and osseointegration of the implant, resulting in implant failure. Ho...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61C19/00G01N1/28G09B23/28
Inventor 孔亮高麒李永锋张永强沈舒宁韶波高媛张述寅孙滢滢王丽华牛强刘青
Owner FOURTH MILITARY MEDICAL UNIVERSITY
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