Acupoint injection biological drug

An acupoint injection and biopharmaceutical technology, applied in the field of medicine, can solve problems such as undiscovered mesenchymal stem cells, and achieve the effects of avoiding the loss of cell activity, simple operation method and long-lasting effect.

Inactive Publication Date: 2012-07-18
任生
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there is no report on the clinical use of mesenchymal stem cells as acupoint injection pharmaceutical preparations

Method used

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  • Acupoint injection biological drug
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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0011] 1. Preparation of biopharmaceuticals

[0012] Mesenchymal stem cells are derived from the umbilical cord of healthy newborns, mixed with normal saline to form a 10mL suspension containing 3×10 cells 7 each; then add 1 mL each of vitamin B1 and vitamin B12 and mix well.

[0013] 2. Clinical trial research

[0014] Take the treatment of cirrhosis of the liver, for example.

[0015] 1. General Information

[0016] Case source: 32 patients with decompensated liver cirrhosis, including 25 patients with post-hepatitis B cirrhosis, 4 patients with alcoholic liver cirrhosis, and 3 patients with schistosomiasis liver cirrhosis. According to Child classification: 6 cases of B grade and 26 cases of C grade. There were 25 males and 7 females, aged 28 to 68 years.

[0017] 2. Diagnosis

[0018] All patients had symptoms and signs such as fatigue, anorexia, abdominal distension, ascites, and lower extremity edema, and the diagnosis of functional indicators was in line with the d...

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PUM

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Abstract

The invention discloses application of mesenchymal stem cells in preparing acupoint injection biological drug and acupoint injection biological drug. The acupoint injection biological drug is composed of physiological saline solution suspension, vitamin B1 and vitamin B12, wherein the volume rate of the suspension : the vitamin B1 : the vitamin B12 is 10-15 : 1-10 : 1-10, and the suspension contains cells of 2*107 to 10*107 per 10mL. The acupoint injection biological drug adopts traditional Chinese medicine methods and formulation design to finish treatment of stem cell technology on diseases, thereby being simple and safe in operation method, obvious and effective in treatment and capable of achieving breakthrough of treatment of stem cell technology on diseases and facilitating development of acupoint injection technology.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a biological agent for acupoint injection. Background technique [0002] Mesenchymal stem cells are a kind of pluripotent stem cells derived from the mesoderm and ectoderm in the early development, which mainly exist in connective tissue and organ mesenchyme, and have multi-lineage differentiation potential, hematopoietic support and promotion of stem cell implantation, immune regulation and Self-replication and other characteristics have been proven to treat many clinically difficult diseases such as advanced liver cirrhosis, diabetic complications, myocardial infarction, and autoimmune diseases. At present, the methods of using mesenchymal stem cells to treat diseases worldwide are usually intravenous injection, arterial injection, and intraspinal injection. However, the intravenous injection takes a long time, and the cells will lose part of their activity during the injecti...

Claims

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Application Information

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IPC IPC(8): A61K35/44A61P1/16A61P3/10A61P9/10A61P31/20A61P37/02A61K31/51A61K31/714A61K35/28
Inventor 任生
Owner 任生
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