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Medicine for treating contagious ecthyma

A technology for canker sore and medicine, applied in the field of veterinary medicine, can solve problems such as unsatisfactory treatment effect, and achieve the effects of preventing secondary bacterial infection, good treatment effect and low price

Inactive Publication Date: 2012-05-09
LANZHOU INST OF VETERINARY SCI CHINESE ACAD OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the common medicines for the treatment of aphthous ulcers are conventional disinfection medicines such as purple syrup and iodine glycerin, and the treatment effect is not satisfactory.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Embodiment 1, the medicine for the treatment of aphthous ulcers disclosed by the present invention is an external spray, which contains 0.025g of ribavirin, 0.0035g of ceftiofur sodium, 2% glycerol and the balance in every milliliter of the medicine of saline. The ribavirin in the medicine of the invention can rapidly inhibit the replication of the aphthous ulcer virus; the ceftiofur sodium in the medicine can prevent the secondary bacterial infection of the ulcer surface of the aphthous ulcer; the glycerin can keep the medicine on the wound surface and slow down the volatilization of the medicine.

[0010] The preparation method of the present invention is as follows: according to the demand, add glycerin, ribavirin and ceftiofur sodium to the physiological saline according to the concentration calculation, fully dissolve, quantify to the target volume, and pack into a spray device for use. If 100ml of medicine is prepared, measure 2ml of glycerin, 2.5g of ribavirin an...

Embodiment 2

[0012] Example 2, every milliliter of medicine contains 0.027g of ribavirin, 0.0038g of ceftiofur sodium, glycerol with a volume concentration of 2.3%, and the rest of normal saline.

[0013] The preparation method is the same as in Example 1.

Embodiment 3

[0014] Example 3, every milliliter of medicine contains 0.028g of ribavirin, 0.004g of ceftiofur sodium, glycerol with a volume concentration of 2.5%, and the rest of normal saline.

[0015] The preparation method is the same as in Example 1.

[0016] The present invention and therapeutic effect thereof are described below by clinical cases.

[0017] Case 1: 30 lambs in a sheep farm in Feidong County, Anhui Province developed mild aphthous ulcer disease.

[0018] Treatment time: August 2010.

[0019] Symptoms: There are papules and blisters on the lips of the lamb.

[0020] Medicine: the medicine of embodiment 1.

[0021] Medication: use the spray twice a day, each time it is better to moisten the wound, use it continuously for three days, and 28 lambs are cured after use.

[0022] Case 2: Moderate aphthous ulcers occurred in 18 lambs in a sheep farm in Dongying, Shandong.

[0023] Treatment time: May 2010.

[0024] Symptoms: There are papules, blisters and scabs on the ...

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PUM

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Abstract

The invention discloses a medicine for treating contagious ecthyma. Each milliliter of the medicine comprises: 0.025-0.028g of ribavirin, 0.0035-0.004g of ceftiofur sodium, glycerin with a volume concentration of 2%-2.5%, and the balance normal saline. The medicine of the invention can rapidly inhibit replication of a contagious ecthyma virus, and prevent an aphthous ulcer surface from developing into secondary bacterial infections. The medicine provided in the invention has the advantages of uneasy volatilization, sufficient sources of medicine components, low price, convenient use, good treatment effect, cure rate up to 75%, lamb mortality declined by 5%, condition improvement rate of 90%, and no harm to breeders.

Description

technical field [0001] The invention belongs to the technical field of animal medicine, in particular to a medicine for treating aphthous ulcer. Background technique [0002] In the breeding industry, it is very common for livestock to have skin lesions, and the mortality rate of some skin lesions is relatively high, such as aphthous ulcer disease, aphthous aphthous ulcer is a zoonotic infectious disease caused by aphthous oral ulcer virus of the parapoxvirus genus. If the secondary infection causes a higher mortality rate of sheep (especially lambs), the data show that the mortality rate of mild canker sores (ie lip type) is about 10%, and moderate canker sore disease (ie lip+eyelid type) ) has a mortality rate of 20%-30%, and the mortality rate of severe aphthous disease (ie lip+hard palate or gingiva type) is 60%-80%. Simultaneously, sheep aphthous disease also seriously threatens the healthy of breeder. [0003] At present, the common medicines for the treatment of aph...

Claims

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Application Information

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IPC IPC(8): A61K31/7056A61K31/546A61P1/02A61P31/20
Inventor 张克山刘湘涛尚佑军田宏尹双辉逯忠新
Owner LANZHOU INST OF VETERINARY SCI CHINESE ACAD OF AGRI SCI
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