Spraying agent for treating asthma and preparation method thereof

Abstract

The invention discloses a spraying agent for treating asthma and a preparation method thereof. The spraying agent contains angelica volatile oil serving as an effective part for relieving asthma, and pharmaceutically allowable auxiliaries, wherein a spraying agent emulsion is prepared through weighing, mixing and setting volume, emulsifying and the like; and 0.2 to 15ml of the angelica volatile oil is contained in each 100ml of the spraying agent emulsion. The angelica volatile oil is easily volatized, has small local irritation, and is more suitable for administration in a local spraying inhalation, so that the medicament can directly reach a pathological position and has quick acting and good curative effect; and less drug is absorbed and enters blood circulation, and the adverse reaction of the whole body is light, so that the spraying agent is more suitable for long-term preventive administration in intermission phase of asthma. The volatile oil has the treatment effect on pulmonary hypertension, pulmonary heart disease, arrhythmia and other complications caused by chronic asthma while overcoming adverse reactions of beta2 receptor agonists and xanthine medicaments.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a spray mainly composed of Chinese angelica volatile oil for the prevention and treatment of bronchial asthma (abbreviated as asthma) and a preparation method thereof. Background technique [0002] The 2006 version of the Global Initiative for Asthma (The Global Initiative for Asthma, GINA) proposed that the global incidence of asthma is 1%-18%, and there are about 300 million asthma patients in the world; the prevalence of asthma in my country is about 2%, and children can According to estimates, there are more than 20 million asthma patients in the country. Asthma has become a major chronic disease that seriously threatens public health. [0003] At present, the chemicals used to treat asthma mainly include glucocorticoids, beta 2 Drugs such as receptor agonists and xanthines have definite and reliable curative effects, but they have...

AI Technical Summary

Problems solved by technology

[0006] However, at present, traditional Chinese medicines such as Angelica sinensis still mostly stay in the application of decoctions, and because most of them are compound preparations with more than ten herbs in practical applications, the preparations are difficult to form and difficult to control; It is very difficult for patients to take

On the other hand, oral preparations such as dripping pills based on Angelica volatile oil must be absorbed by the body into the blood circulation and reach the corresponding parts to play a therapeutic role, so that the amount of medicine arriving at the site of action is relatively small, and the onset of action is slow and the curative effect is poor; Drug concentrations in other parts are relatively high and adverse reactions are prone to occur

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