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New application of citron daylily and citron daylily general flavone

A technology of daylily and total flavonoids, which is applied in the field of new uses and preparation of daylily and total flavonoids of daylily, and can solve problems such as unreported application research.

Active Publication Date: 2011-10-12
倪健
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are few studies on the extraction of total flavonoids from daylily, and no reports on its application

Method used

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  • New application of citron daylily and citron daylily general flavone
  • New application of citron daylily and citron daylily general flavone
  • New application of citron daylily and citron daylily general flavone

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0151] Embodiment 1: Capsules

[0152]Cut 9900g of dried day lily into 2-3 cm long sections, soak in 95% ethanol overnight. Heating and extracting with 95% ethanol for 3 times, timing from boiling, the time is 40min, 30min, 30min respectively, filtering, combining the filtrates, recovering ethanol, and obtaining extract A. The residue was heated and extracted twice with 60% ethanol for 40 minutes each time, filtered, the filtrates were combined, and the ethanol was recovered to obtain the extract B. Dilute the extract A with distilled water, filter, pass through the treated AB-8 macroporous resin column, wash with distilled water until the effluent is transparent, elute with 60% ethanol for 3 times the column volume, recover the ethanol, and obtain sample 1. Treat extract B in the same way to get sample 2. Sample 1 is 64.3101g, and Sample 2 is 60.9338g. The extract yield is greater than 1.265%. Take the dried extract, add lactose (or starch, or dextrin) at a ratio of 1:0-5,...

Embodiment 2

[0156] Embodiment 2: Preparation and inspection of total flavonoids in day lily

[0157] Cut 9900g of dried day lily into 2-3 cm long sections, soak in 95% ethanol overnight. Heating and extracting with 95% ethanol for 3 times, timing from boiling, the time is 40min, 30min, 30min respectively, filtering, combining the filtrates, recovering ethanol, and obtaining extract A. The residue was heated and extracted twice with 60% ethanol for 40 minutes each time, filtered, the filtrates were combined, and the ethanol was recovered to obtain the extract B. Dilute the extract A with distilled water, filter, pass through the treated AB-8 macroporous resin column, wash with distilled water until the effluent is transparent, elute with 60% ethanol for 3 times the column volume, recover the ethanol, and obtain sample 1. Treat extract B in the same way to get sample 2. Sample 1 is 64.3101g, and Sample 2 is 60.9338g. The cream yield is greater than 1.265%, and samples 1 and 2 are mixed t...

Embodiment 3

[0163] Embodiment 3: Granules

[0164] Cut 9900g of dried day lily into 2-3 cm long sections, soak in 95% ethanol overnight. Heating and extracting with 95% ethanol for 3 times, timing from boiling, the time is 40min, 30min, 30min respectively, filtering, combining the filtrates, recovering ethanol, and obtaining extract A. The residue was heated and extracted twice with 60% ethanol for 40 minutes each time, filtered, the filtrates were combined, and the ethanol was recovered to obtain the extract B. Dilute the extract A with distilled water, filter, pass through the treated AB-8 macroporous resin column, wash with distilled water until the effluent is transparent, elute with 60% ethanol for 3 times the column volume, recover the ethanol, and obtain sample 1. Treat extract B in the same way to get sample 2. Sample 1 is 64.3101g, and Sample 2 is 60.9338g. The paste yield is greater than 1.265%. Samples 1 and 2 are mixed, and dextrin is added to make granules through a conven...

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Abstract

The invention relates to new application of citron daylily and citron daylily general flavone, and discloses application of citron daylily and citron daylily general flavone to the preparation of medicaments for resisting depression, an particularly discloses application of citron daylily and citron daylily general flavone to the preparation of medicaments for rising serotonin, norepinephrine, dopamine and 5-hydroxyindolacetic acid in cerebral cortex, and discloses application of citron daylily and citron daylily general flavone to the preparation of medicaments for antagonistic reserpine. The application is verified by pharmacological experiments.

Description

[0001] The present invention is a divisional application, the original application number is 200810135327.4, the original application date is July 31, 2008, and the original application name is the new application of day lily and total flavonoids of day lily. technical field [0002] The invention relates to a new application of a traditional Chinese medicine and its effective parts, in particular to a new application of day lily and total flavonoids of day lily and a preparation method thereof. Background technique [0003] Day lily is also known as "day lily", "lily of the day", commonly known as forget care grass. It is a plant of the genus Hemerocallis in the family Liliaceae and has rich nutritional ingredients. Its main chemical components are protein, fat, carbohydrates, as well as various vitamins, alkaloids, glycosides, flavonoids, carotene, volatile oil, tannin, and inorganic minerals calcium and phosphorus. According to the "Dictionary of Traditional Chinese Medi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P25/24A61P43/00
Inventor 邹忆怀倪健朱陵群
Owner 倪健
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