Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Novel application of alchornea trewioides extract in pharmacy

A technology of red-backed mountain hemp stalks and extracts, which is applied in the medical application field of plant extracts, and can solve problems such as renal parenchyma damage, kidney toxicity and side effects, and treating symptoms but not the root cause

Inactive Publication Date: 2011-10-05
GUANGXI INST OF BOTANY THE CHINESE ACAD OF SCI
View PDF3 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine mostly uses antibiotics for treatment, many of which have toxic and side effects on the kidneys, such as gentamicin, kanamycin, flufenacin, etc. If the treatment is not done properly, it may cause serious damage to the kidney parenchyma, or even renal failure
At the same time, some of the existing drugs treat the symptoms but not the root cause, so there is a great need on the market for drugs that are effective and non-toxic for the treatment of this type of disease
At present, there is no public report on the use of red-backed mountain hemp stalk as a single or compound prescription for the treatment of non-bacterial prostatitis and benign prostatic hyperplasia

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Novel application of alchornea trewioides extract in pharmacy
  • Novel application of alchornea trewioides extract in pharmacy
  • Novel application of alchornea trewioides extract in pharmacy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] 1) Take the original medicinal material (dry medicinal material) of the whole plant of the stalk of the red back mountain, pulverize it, and set aside;

[0022] 2) Weigh 5 kg of crushed medicinal material, add water to decoct and extract three times, the amount of water added is 8 times, 5 times, and 4 times the weight of the medicinal material respectively, and the extraction time is 2 hours, 1.5 hours, and 1.5 hours respectively. Combine the filtrates, concentrate to the extract, and freeze-dry to obtain the water extract of the red-backed mountain hemp stalk.

Embodiment 2

[0024] 1) Take the roots and leaves (dried medicinal materials) of the red-backed mountain hemp, crush them, and set aside;

[0025] 2) Weigh 5 kg of pulverized medicinal material, add 10% ethanol and extract three times, the amount of solvent is 8 times, 5 times, and 4 times of the weight of the medicinal material respectively, and the extraction time is 2 hours, 1.5 hours, and 1.5 hours respectively. Combine the filtrates, recover until there is no alcohol smell, and dry under reduced pressure to obtain the ethanol extract of the red-backed mountain hemp stalk.

Embodiment 3

[0027] 1) Take the stalks and leaves (dry medicinal materials) of the red-backed mountain hemp, crush them, and set aside;

[0028] 2) Weigh 5 kg of pulverized medicinal materials, add 60% ethanol to extract three times, the amount of solvent is 8 times, 4 times and 3 times of the weight of medicinal materials respectively, and the extraction time is 2 hours, 1.5 hours and 1.5 hours respectively. Combine the filtrates, recover until there is no alcohol smell, and dry under reduced pressure to obtain the ethanol extract of the red-backed mountain hemp stalk.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a novel application of an alchornea trewioides extract in the pharmacy field, and in particular, an application of an alchornea trewioides extract in preparing drugs for treating nonbacterial prostatitis; and an application of an alchornea trewioides extract in preparing drugs for treating nonbacterial prostatic hyperplasia; In addition, the invention also discloses a drug composition for treating nonbacterial prostatitis and prostatic hyperplasia with the alchornea trewioides extract as an active component. Through experiment, the applicant finds that the alchornea trewioides extract can significantly decrease the prostate wet weight and the prostate index of a model animal, has a good inhibition effect on prostate glandular swelling of a nonbacterial prostatitis model rat, can improve blood circulation and promote the softening of the prostate glandular texture, and can mitigate interstitial hyperemia, edema, inflammatory cell infiltration and cell degeneration of prostate cells. Compared with existing and common western medicine, the alchornea trewioides extract has comparable or even better efficacy and less toxicity, and is safer for medication.

Description

technical field [0001] The invention relates to the field of medical application of plant extracts, in particular to a new pharmaceutical application of the extract of the red-backed mountain hemp stalk. Background technique [0002] Prostatitis and benign prostatic hyperplasia are common and refractory diseases of the genitourinary system in middle-aged and elderly people, with a high incidence rate. According to clinical statistics, the number of outpatient visits accounts for about 25% of male genitourinary system disease outpatient visits. High attention is also one of the key points and difficulties in community health work. The treatment of this disease often adopts traditional Chinese medicine or Western medicine treatment at present, and the traditional Chinese medical science is mostly according to the basic treatment principle of clearing the benefit and eliminating pathogenic factors for the excess, and invigorating the kidney and strengthening the body for the d...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/47A61P13/08A61K125/00A61K127/00
Inventor 陈月圆黄永林文永新李典鹏卢凤来刘金磊
Owner GUANGXI INST OF BOTANY THE CHINESE ACAD OF SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com