Magnetic field intensity controllable electrochemical immune sensor

Abstract

The invention relates to a magnetic field intensity controllable electrochemical immune sensor, which consists of an electrode device and an operating device. Generation and vanish of the magnetic field of an electrode in the electrode device are adjusted through the operating device; and when the magnetic field is generated, the electrochemical immune sensor is used for quantitative detection of target biological molecules. The electrochemical immune sensor can be reused, has simple structure, is convenient for preparation, and can effectively and quantitatively detect the biological molecules. The electrochemical immune sensor has long service life, the using times of the electrochemical immune sensor greatly exceeds 10 times, and the detection result is accurate; and the electrochemical immune sensor has the advantages of simple structure, low cost and the like.

Description

technical field [0001] The invention relates to an electrochemical immunosensor, in particular to an electrochemical immunosensor with controllable magnetic field strength. Background technique [0002] Electrochemical immunosensor is an immunoassay method that combines immunoassay technology with electrochemical sensors. It is a biosensor based on measuring current and potential changes for immunoassay. Electrochemical immunosensors have important applications in clinical medicine, the environment, and the food industry, and have become current due to their advantages of small size, strong specificity, high sensitivity, fast and convenient detection, low cost, and easy real-time online living detection. One of the hotspots of research. [0003] Electrochemical immunosensors are usually composed of sensitive elements (biological materials), conversion elements (electrodes), electrolytic cells, and data acquisition and processing systems. Quantitative detection is achieved b...

AI Technical Summary

Problems solved by technology

The conventional electrochemical immunosensor with controllable magnetic field intensity is modified on the electrode surface to immobilize functional molecules, such as antibodies, antigens, enzymes and other substances on the electrode surface, so as to achieve a specific response to the measured substance. It is necessary to regenerate the immunosensor, that is, to remove the measured substances bound to the surface of the electrode. Certain chemical conditions, such as acidic conditions and alkaline conditions, are required to destroy the antigen-antibody combination. At the same time, the stability of the electrode modification and the modification on the electrode The activity of functional molecules on the surface has a certain impact, which reduces the performance of the sensor, shortens its service life, and limits its use times

Therefore, although the electrodes in conventional electrochemical immunosensors can be reused many times, the number of times they can be reused generally does not exceed 10 times, and as the number of times of use increases, the performance of the working electrode will also decrease sharply, seriously affecting The validity of the detection is improved; and the electrode preparation process is complicated and the production cost is high

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