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Sinomenine medicine resin slow-release suspension and preparation method thereof

A technology of sinomenine hydrochloride and sustained-release suspension, which is applied in the field of medicine and can solve problems such as inconvenience, pain, and frequent use of medication

Inactive Publication Date: 2011-08-17
普尔药物科技开发(深圳)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the injection avoids gastrointestinal adverse reactions, it is inconvenient and painful for patients to take medicine;

Method used

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  • Sinomenine medicine resin slow-release suspension and preparation method thereof
  • Sinomenine medicine resin slow-release suspension and preparation method thereof
  • Sinomenine medicine resin slow-release suspension and preparation method thereof

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Embodiment Construction

[0035] The technical scheme of the present invention is further set forth below in conjunction with the data of embodiment and prescription research, verification:

[0036] The invention relates to a sinomenine hydrochloride medicinal resin sustained-release suspension and a preparation method thereof.

[0037] 1. Prescription composition and preparation process

[0038] 1.1 Prescription

[0039] Sinomenine Hydrochloride 217g

[0040] JK 006 cation exchange resin 783g

[0041]

[0042] Sinomenine Hydrochloride Drug Resin Complex 1000g

[0043] Sinomenine Hydrochloride Drug Resin Complex 1000g

[0044] Acrylic RS100 80g

[0045] Macrogol 400 12g

[0046] Carbomer 934P 1000g

[0047] Distilled water 100L

[0048]

[0049] Makes 1000 bottles

[0050] 1.2 Preparation process

[0051] Weigh 217g of sinomenine hydrochloride and add water to dissolve it into 12mg·mL -1 Then weigh 783...

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Abstract

The invention discloses a sinomenine medicine resin slow-release suspension which is prepared by a sinomenine medicine resin micro-capsule and a pharmaceutical common suspensions; the sinomenine medicine resin micro-capsule is made from a sinomenine medicine resin and a coating material; and the coating material is a medical high molecular material or a high molecular insoluble medical auxiliary material with good water permeability. The invention further discloses a preparation method of the sinomenine medicine resin slow-release suspensions. The sinomenine medicine resin slow-release suspension has the good effects of being large in medicine carrying quantity and high in medicine use ratio.

Description

technical field [0001] The invention relates to a sinomenine hydrochloride medicinal resin sustained-release suspension and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] Sinomenine hydrochloride is the hydrochloride salt of the alkaloid monomer sinomenine extracted from the traditional Chinese medicine Qingfengteng. It has anti-inflammatory, analgesic, immunosuppressive, antihypertensive, antiarrhythmic and other pharmacological effects. At present, Zhengqing Fengtongning Tablets and Zhengqing Fengtongning Injection have been used clinically to treat various rheumatic diseases such as rheumatic joint pain and antiarrhythmia, and have achieved good curative effect. [0003] Sinomenine has anti-inflammatory, analgesic and anti-arrhythmic effects. Clinically, it is mainly used in the treatment of various rheumatic diseases and cardiovascular diseases. In particular, it is widely used in the treatment of rheumatism an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/10A61K31/485A61K47/48A61K47/34A61K47/32A61P29/00A61P19/02A61P19/04A61P9/06A61K47/10A61K47/26
Inventor 周桂莲周伟刘姹杨大坚陈新滋
Owner 普尔药物科技开发(深圳)有限公司
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