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Dual-cordis effect of Xin Keshu

A curative effect, coronary heart disease technology, applied in cardiovascular system diseases, medical preparations containing active ingredients, plant raw materials, etc. The effect of improving mood and reducing adverse reactions

Active Publication Date: 2011-08-10
SHANDONG WOHUA PHARMACEUTICALS CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] There are three main types of adverse emotions such as anxiety and depression associated with coronary heart disease: (1) The patient has a lot of mental stress at work, has some symptoms of chest tightness and chest pain, suspects heart disease, and is anxious, but there is no organic heart disease at all after examination evidence of
(2) The patient has symptoms of chest tightness and palpitations, and the electrocardiogram shows only premature beats or mild ST-T changes. There is no serious structural heart disease, and the prognosis is good. However, the patient's heart disease is not serious due to the doctor's incorrect explanation. , heavy mental stress
(3) For patients with organic heart disease, patients who have undergone coronary artery intervention surgery, coronary artery bypass surgery, and cardiac pacemaker implantation surgery, the surgical treatment is very successful, but the first aid, surgery, The death of the patient and other shocks, as well as various discomforts after the illness, coupled with ignorance and ignorance of the prognosis of the disease, lead to spiritual trauma, depression, anxiety and other mental and psychological disorders, leading to aggravated prognosis and worsened quality of life Wait

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] The preparation of embodiment 1 tablet

[0072] [Prescription] Pueraria 600g, Hawthorn 600g, Salvia miltiorrhiza 600g, Panax notoginseng 40g, Woody fragrance 40g

[0073] [Preparation method] 1 / 3 hawthorn, panax notoginseng, and woody fragrance are crushed into fine powder, and the remaining hawthorn and kudzu root are soaked in 60% ethanol for 30 minutes, heated and refluxed twice, the first time is 2.5 hours, and the second time is 2 hours , combine the ethanol extracts, recover ethanol under reduced pressure, filter, and the filtrate is set aside; decocting red ginseng in water twice, the first time for 2 hours, and the second time for 1.5 hours, combine the decocting liquid, filter, and mix the above filtrate with decocting The cooking liquid is mixed evenly and concentrated to a relative density of 1.24 to 1.26 (measured at 75°C to 80°C). Mix the extract and fine powder, make granules, dry, compress into tablets, and coat.

Embodiment 2

[0074] The preparation of embodiment 2 capsules

[0075] [Prescription] Pueraria 600g, Hawthorn 600g, Salvia miltiorrhiza 600g, Panax notoginseng 40g, Woody fragrance 40g

[0076] [Preparation method] 1 / 3 hawthorn, panax notoginseng, and woody fragrance are crushed into fine powder, and the remaining hawthorn and kudzu root are soaked in 60% ethanol for 30 minutes, heated and refluxed twice, the first time is 2.5 hours, and the second time is 2 hours , combine the ethanol extracts, recover ethanol under reduced pressure, filter, and the filtrate is set aside; decocting red ginseng in water twice, the first time for 2 hours, and the second time for 1.5 hours, combine the decocting liquid, filter, and mix the above filtrate with decocting The cooking liquid is mixed evenly and concentrated to a relative density of 1.24 to 1.26 (measured at 75°C to 80°C). Mix the extract and fine powder, make granules, and pack into capsules.

Embodiment 3

[0077] The preparation of embodiment 3 dispersible tablets

[0078] [Prescription] Pueraria 300g, Hawthorn 300g, Salvia 300g, Panax notoginseng 20g, Muxiang 20g

[0079] [Preparation method] 1 / 3 hawthorn, panax notoginseng, and woody fragrance are crushed into fine powder, and the remaining hawthorn and kudzu root are soaked in 60% ethanol for 30 minutes, heated and refluxed twice, the first time is 2.5 hours, and the second time is 2 hours , combine the ethanol extracts, recover ethanol under reduced pressure, filter, and the filtrate is set aside; decocting red ginseng in water twice, the first time for 2 hours, and the second time for 1.5 hours, combine the decocting liquid, filter, and mix the above filtrate with decocting The cooking liquid is mixed evenly and concentrated to a relative density of 1.24 to 1.26 (measured at 75°C to 80°C). Mix the extract and fine powder, make granules, dry, compress into tablets, and coat.

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Abstract

The invention relates to a new curative application of a traditional Chinese medicine, in particular to the dual-cordis effect treatment of Xin Keshu as a traditional Chinese medicine. The traditional Chinese medicine has new curative application to patients accompanied with adverse moods, such as worry, depression, and the like.

Description

Technical field: [0001] The invention relates to a new therapeutic application of a traditional Chinese medicine, in particular to the treatment of the dual-heart effect of the traditional Chinese medicine Xinkeshu. Background technique: [0002] Xinkeshu is a traditional Chinese medicine preparation for promoting blood circulation, removing blood stasis, promoting qi and relieving pain. Its formula is composed of hawthorn, kudzu root, salvia miltiorrhiza, notoginseng, and woody fragrance. It is used for chest tightness, dizziness, headache, neck pain, arrhythmia, hyperlipidemia, etc. caused by qi stagnation and blood stasis type coronary heart disease. There are currently tablets, capsules, granules and other dosage forms on the market in China. [0003] Xinkeshu Tablet [Prescription] Pueraria 600g, Hawthorn 600g, Salvia 600g, Panax notoginseng 40g, Muxiang 40g [0004] The preparation of Xinkeshu tablet comprises the following steps, [0005] 1) 1 / 3 of the amount of haw...

Claims

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Application Information

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IPC IPC(8): A61K36/734A61P3/06A61P9/10
Inventor 曾英姿周万辉赵磊于洪亮
Owner SHANDONG WOHUA PHARMACEUTICALS CO LTD
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