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Compound pink plumepoppy herb injection for treating calf diarrhea and preparation method thereof

A calf diarrhea and injection technology, applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, and resistance to vector-borne diseases, can solve problems such as high mortality, inconvenience for breeders, and complicated infection, and achieve preparation The method has the advantages of simple process, avoiding too long treatment time, and widening the range of disease resistance

Inactive Publication Date: 2011-02-09
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Due to the widespread occurrence of such diseases recently, the pathogen cannot be accurately determined and the pathogen is ubiquitous, resulting in complicated and diversified infections, rapid disease progression, and high mortality rates. Simple treatment with conventional methods and drugs is often adopted, which is basically untreatable. After the disease is determined, due to the problem of drug combination, collocation and drug resistance, it will cause inconvenience to the majority of farmers, the disease cannot be well controlled, and the treatment time is not timely
During the course of treatment, dehydration may be caused by too long treatment time, insensitivity of medicines, changing medicines in the middle, or weakness and severe decline of resistance caused by too long treatment time, which may cause other infections, acid-base poisoning, etc. Calves that lead to death or stunted growth after healing can easily cause great losses

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] (1) Take 30 L of water for injection, add 6 kg of sodium salicylate, stir to dissolve, then add 1 kg ofloxacin and 2 kg of acetylmethaquine in sequence, and stir until completely dissolved.

[0020] (2) Take 20L of dimethylformamide, add 3kg of Boluohui extract, and stir to dissolve.

[0021] (3) Combine the prepared solution of step (1) and step (2), add 20L of 95% ethanol, stir well, add 5L of analytically pure hydrochloric acid with a mass percentage of 37%, after stirring well, add water for injection to 100L, Stir evenly and keep it for 15-20min. After the medicinal liquid becomes clear, it will be made into compound boluohui injection for treating calf diarrhea.

Embodiment 2

[0023] (1) Take 30 L of water for injection, add 24 kg of sodium salicylate, stir to dissolve, then add 7 kg ofloxacin and 8 kg of acetylmethaquine in sequence, and stir until completely dissolved.

[0024] (2) Take 20L of dimethylformamide, add 0.2kg of Boluohui extract, and stir to dissolve.

[0025] (3) Combine the prepared solution of step (1) and step (2), add 20L of 95% ethanol, stir well, add 5L of analytically pure hydrochloric acid with a mass percentage of 37%, after stirring well, add water for injection to 100L, Stir evenly and keep it for 15-20min. After the medicinal liquid becomes clear, it will be made into compound boluohui injection for treating calf diarrhea.

Embodiment 3

[0027] (1) Take 30 L of water for injection, add 9 kg of sodium salicylate, stir to dissolve, then add 3 kg ofloxacin and 3 kg of acetylmethaquine in sequence, and stir to dissolve.

[0028] (2) Take 20L of dimethylformamide, add 1.5kg of Boluohui extract, and stir to dissolve;

[0029] (3) Combine the prepared solution of step (1) and step (2), add 20L of 95% ethanol, stir well, add 5L of analytically pure hydrochloric acid with a mass percentage of 37%, after stirring well, add water for injection to 100L, Stir evenly and keep it for 15-20min. After the medicinal liquid becomes clear, it will be made into compound boluohui injection for treating calf diarrhea.

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PUM

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Abstract

The invention discloses compound pink plumepoppy herb injection for treating diarrhea of calves and a preparation method thereof. The invention aims to provide quick-response compound pink plumepoppy herb injection for treating diarrhea of the calves infected with one or more of Escherichia coli, clostridium welchii, salmonella, mycoplasma and the like and a simple-process and easily-implemented preparation method thereof. 100 liters of the injection comprises 0.2 to 3 kilograms of pink plumepoppy herb extract, 2 to 8 kilograms of mequindox, 1 to 7 kilograms of ofloxacin, 6 to 24 kilograms of sodium salicylate, 20 liters of dimethylformamide, 20 liters of 95 percent ethanol, 5 liters of hydrochloric acid and the balance of injection water. In the compound pink plumepoppy herb injection, the medicaments are reasonably proportioned; an antibacterial spectrum is expanded as big as possible; pathogenic microorganisms are killed pertinently; medicament resistance is effectively reduced; the response is quick; clinical symptoms can be remitted in the occurrence of the diarrhea of the calves; and the conditions of death of the calves, dysontogenesis after the calves are cured and the like are avoided.

Description

technical field [0001] The invention relates to a compound Boluohui injection for treating calf diarrhea and a preparation method thereof. Background technique [0002] Calf diarrhea is an important disease that causes the death of calves. The pathogens include one or more infections such as Escherichia coli, Clostridium welchii, Salmonella, and mycoplasma. The main clinical symptoms are severe diarrhea in calves, with blood or no blood in the feces , mixed with air bubbles, the color is yellow, yellow-green or off-white, etc., the sick cow is bowed, incontinent, and some defecate like a jet, polluting around the anus, the sick cow has indigestion, extreme pain, often causes dehydration and exhaustion and dies. [0003] Due to the widespread occurrence of such diseases recently, the pathogen cannot be accurately determined and the pathogen is ubiquitous, resulting in complicated and diversified infections, rapid disease progression, and high mortality rates. Simple treatment...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61P1/12A61K31/60A61K9/08A61K31/498A61K36/66A61K31/5383A61P31/04
CPCY02A50/30
Inventor 徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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