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Effective part composite containing salvia miltiorrhiza bunge and panax pseudoginseng and preparation method and application thereof

A technology of effective parts and compositions, applied in the field of traditional Chinese medicine, can solve the problems of ineffective use of active ingredients, difficulty in opening the international market, and inability to occupy the market.

Inactive Publication Date: 2010-12-15
JIANGXI HERBFINE HI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the preparations for the treatment of similar diseases on the market have not solved the problems of large dosage, low bioavailability, poor controllability of quality standards, and ineffective utilization of active ingredients. The technology is basically traditional technology, and there is nothing new The introduction of technology cannot occupy enough market, and it is even more difficult to open the international market

Method used

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  • Effective part composite containing salvia miltiorrhiza bunge and panax pseudoginseng and preparation method and application thereof
  • Effective part composite containing salvia miltiorrhiza bunge and panax pseudoginseng and preparation method and application thereof
  • Effective part composite containing salvia miltiorrhiza bunge and panax pseudoginseng and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A composition containing effective parts of Danshen and Panax notoginseng, the weight ratio of the components of medicinal materials used is:

[0026] 10 parts of total phenolic acid of salvia miltiorrhiza, 20 parts of tanshinone, 10 parts of total saponins of Panax notoginseng

[0027] 50 parts of total flavonoids of balsamic oil and 10 parts of total terpenes of balsamic oil.

[0028] A preparation method of a composition containing salvia miltiorrhiza and effective parts of Panax notoginseng, the preparation method comprising the following steps:

[0029] A, the preparation method of total phenolic acid of salvia miltiorrhiza with a content of more than 50% by weight: refining the water extract of salvia miltiorrhiza medicinal material through macroporous adsorption resin, eluting with water first, discarding the washing liquid, eluting with ethanol again, collecting the eluent, Concentrate under reduced pressure and dry to obtain.

[0030] B. The preparation metho...

Embodiment 2

[0038] A composition containing effective parts of Danshen and Panax notoginseng, the weight ratio of the components of medicinal materials used is:

[0039] 50 parts of total salvia phenolic acid 50 parts of Panax notoginseng saponins

[0040] 10 parts of total flavonoids of balsamic oil and 20 parts of total terpenes of balsamic oil.

[0041] Its preparation method and use are consistent with Example 1.

Embodiment 3

[0043] A composition containing effective parts of Danshen and Panax notoginseng, the weight ratio of the components of medicinal materials used is:

[0044] 99 parts of total phenolic acid of salvia miltiorrhiza, 20 parts of tanshinone, 99 parts of total saponins of Panax notoginseng

[0045] 20 parts of total terpenes of balsamic oil.

[0046] Its preparation method and use are consistent with Example 1.

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Abstract

The invention relates to an effective part composite containing salvia miltiorrhiza bunge and panax pseudoginseng effective parts and a preparation method thereof and also relates to application of a drug prepared from the effective part composite in preventing and curing cardiovascular and cerebrovascular diseases, senile dementia, cerebral infarction, cerebral ischemia and other various diseases caused by cerebral ischemia, belonging to the technical field of traditional Chinese medicine. The composite comprises the following drug components in parts by weight: 10-99 parts of total salvianolic acid, 0-50 parts of tanshinone, 10-99 parts of panax notoginseng saponins, 0-50 parts of dalbergia wood general flavone and 0-20 parts of dalbergia wood oil total terpenoid. The effective part composite containing salvia miltiorrhiza bunge and panax pseudoginseng, which is disclosed by the invention, has better action of resisting myocardial ischemia, has certain action of resisting thrombopoiesis and anticoagulation, improves peroxide of cardiac muscular tissues during myocardial ischemia resistance, improves medical hemorheology and performs the efficacy of paths which affect clotting functions.

Description

technical field [0001] The present invention relates to a composition containing salvia miltiorrhiza and Panax notoginseng effective fractions and a preparation method thereof; and the medicine prepared from the effective fraction composition is effective in preventing and treating cardiovascular and cerebrovascular diseases, senile dementia, cerebral infarction, cerebral ischemia and those caused by cerebral ischemia It is applied in various other disease medicines, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Cardiovascular disease is a common and frequently-occurring disease that middle-aged and elderly people are susceptible to, and it seriously endangers human health. Among them, the number of cases of coronary heart disease in my country exceeds 1 million per year, and the incidence of coronary heart disease presents an increasing trend year by year. According to epidemiological studies, the mortality rate of cardio...

Claims

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Application Information

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IPC IPC(8): A61K36/537A61P9/00A61P25/28A61P9/10A61K31/58
Inventor 范玫玫杨世林简晖王金钱张爱玲魏惠珍钱霞胡宏辉
Owner JIANGXI HERBFINE HI TECH
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