Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Multi-path, multi-magnification, non-confocal fluorescence emission endoscopy apparatus and methods

A fluorescence emission, endoscopy technology, applied in the direction of analysis, endoscopy, optics, etc. using fluorescence emission, can solve problems such as insufficient signal collection and/or transmission, image blockage, etc., to achieve simplicity and reduce image blockage. Effect

Active Publication Date: 2010-12-08
CORNELL UNIVERSITY
View PDF3 Cites 22 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] The present inventors have also recognized that conventional confocal-based endoscopic imaging devices and methods have disadvantages, such as due to image occlusion from scanning devices and insufficient signal collection and / or transmission via concentric excitation fiber-optic waveguides

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Multi-path, multi-magnification, non-confocal fluorescence emission endoscopy apparatus and methods
  • Multi-path, multi-magnification, non-confocal fluorescence emission endoscopy apparatus and methods
  • Multi-path, multi-magnification, non-confocal fluorescence emission endoscopy apparatus and methods

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0035] Embodiments of the invention generally relate to fluorescence emission endoscopy systems and methods.

[0036] figure 1 A schematic diagram of a coaxial endoscopic system 100-1 is shown, shown with a distal section 101 containing an optical system embodied by the present invention. As used herein, the distal section may be the distal section of an endoscope, or alternatively, may be a biopsy needle. The system is coaxial because, as shown, the fiber optic 159 that provides near-IR target excitation light is partially coaxially surrounded by the light-transmissive interior of the distal section 101 . Fluorescence emission endoscopy system 100-1 includes an illumination platform 105 that includes a suitable fluorescence emission excitation source, such as a femtosecond, pulsed laser, and visible target illumination source. The illumination platform control module 107 provides, for example, pulse shape control, beam expansion, spatial filtering, spectral phase control, m...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

Embodiments of the invention include an optical system and an optical system module, coupled to a distal end of a fluorescence emission endoscope apparatus, an optical waveguide-based fluorescence emission endoscopy system, and a method for remotely- controlled, multi -magnification imaging of a target or fluorescence emission collection from a target with a fluorescence emission endoscope apparatus. An exemplary system includes an objective lens disposed in a distal end of an endoscope apparatus. The lens is adapted to transmit both a visible target illumination and a fluorescence-emission-inducing target illumination as well as fluorescence-emission and visible light from the target. Thee system can thus simultaneously provide low magnification, large field of view imaging and high magnification, high-resolution multiphoton imaging with a single lens system.

Description

[0001] Cross References to Related Applications [0002] This application claims priority to U.S. Provisional Application S / N 60 / 987,868, filed November 14, 2007, and U.S. Provisional Application S / N 60 / 987,270, filed November 12, 2007, the entirety of the subject matter of these applications is incorporated herein by reference. [0003] Statement Regarding Federally Funded Research or Development [0004] This invention was made with government support under Project Nos. 1R01EB006736-01 and 5-P41EB001976 funded by the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health. technical field [0005] Embodiments of the present invention relate most generally to the field of multiphoton fluorescence and / or nonlinear harmonic emission endoscopic devices and methods. In particular, embodiments of the present invention relate to multi-magnification, non-confocal, multi-path optical systems and optical system modules for fluorescence emissi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61B1/00A61B1/07
CPCA61B5/0071A61B5/0062A61B1/043A61B1/00165A61B5/0086A61B1/00172A61B1/00096A61B1/00188A61B1/0638A61B1/07G02B13/146G02B23/243G02B21/04G02B26/103
Inventor W·W.·韦布C·徐
Owner CORNELL UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com