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Method for producing hollow suppository by utilizing rotary mold

A rotating mold and hollow technology, which is applied in the direction of making medicines into special physical or ingestible devices, can solve problems such as material waste, achieve the effects of reducing costs, saving materials, and improving production efficiency

Active Publication Date: 2010-10-13
WUHAN ZHENGTONG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problem of excessive material waste in the manufacturing process of hollow plugs in the above-mentioned background technology, and propose a method for producing hollow plugs using a rotary mold, so as to make the manufacture of hollow plugs more economical and environmentally friendly, and realize mechanization and automation , to meet the requirements of mass production

Method used

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  • Method for producing hollow suppository by utilizing rotary mold
  • Method for producing hollow suppository by utilizing rotary mold
  • Method for producing hollow suppository by utilizing rotary mold

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] (1), perfusion: Utilize existing suppository filling machine, the fat-soluble matrix or water-soluble matrix that melts is poured in each cavity 7 of suppository shell 1, see figure 1 , figure 2 ;

[0031] (2), rotary mold forming hole: insert rotary mold 8 in each capsule cavity 7 of suppository shell before matrix solidifies completely, rotary mold 8 is driven by power unit to rotate in matrix, until the matrix in suppository shell capsule cavity is completely After solidification, the rotary mold is lifted to form a hollow cavity 4 in the matrix of the suppository shell cavity.

[0032] Rotary mold 8 rotating speed control is when rotating mold is extracted from the suppository shell that contains matrix, does not adhere on the rotary mold, or very little adhesion matrix is ​​a standard, and now the rotating speed is 100~200 revolutions per minute.

[0033] The rotary mold 8 is a cylinder rotating along the axis, and the end of the cylinder is in the shape of a sp...

Embodiment 2

[0038] This embodiment is basically the same as Embodiment 1, the difference is that the rotary mold 8 is a solid cylinder rotating along the axis, there is no cold air blind hole inside, and the end of the cylinder is spherical. In the hole forming process of the rotary mold, after the matrix is ​​completely solidified, insert the rotary mold driven by the power device at a speed of more than 7,000 revolutions per minute into the cavity of the suppository shell. During the hole forming process, the rotary mold rotates at high speed while extending into the solidified matrix, and after the matrix in the cavity of the suppository shell forms a hollow cavity, lift the rotary mold. No waste matrix is ​​generated during this process.

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Abstract

The invention relates to a method for producing a hollow suppository by utilizing a rotary mold, which comprises the following steps: firstly, filling a melted medium in a suppository shell cavity by a suppository filling machine; inserting the rotary mold in the suppository shell cavity, and allowing the rotary mold to be driven by a power device to rotate in the medium; after the medium in the suppository shell cavity forms a hollow cavity, lifting the rotary mold; filling quantitative drugs in the hollow cavity; and sealing with the same medium, and obtaining the drug-containing hollow suppository. The method for producing the hollow suppository by utilizing the rotary mold can not only ensure the production quality of the hollow suppository, substantially improve productivity and achieve the mechanized and automatic production of the hollow suppository, but also save materials and reduce cost in the preparation process.

Description

technical field [0001] The invention relates to a production method of a medicinal suppository, in particular to a method for producing a hollow suppository by using a rotary mold. Background technique [0002] Hollow suppository is a new type of suppository invented by the Japanese in the 1970s, but it has not been industrialized. In recent years, there have been many research reports on hollow suppository in China, and most of them focus on the pharmacodynamic research of hollow suppository with ordinary suppository and the same drug. . At present, the production of hollow plugs mostly adopts manual mold preparation or the method of pouring out the unsolidified part of ordinary plugs in a semi-solidified state to prepare hollow plugs. These two methods are slow in preparing hollow plugs and difficult to guarantee quality. [0003] Before the filing of this application, the applicant applied to the China Intellectual Property Office on July 21, 2009 for an invention patent...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61J3/08
Inventor 韩昌志
Owner WUHAN ZHENGTONG PHARMA CO LTD
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