Application of composite containing polygonum orientale in preparing medicaments for preventing and treating diabetes and complication thereof
A technology for diabetes and composition, which can be used in medical preparations containing active ingredients, drug combinations, metabolic diseases, etc., and can solve problems such as no diabetes prevention and treatment effect.
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Embodiment 1
[0092] 5 parts of Chinese Radix, 4 parts of hawthorn leaves, 3 parts of Panax notoginseng and 3 parts of Rhizoma Chuanxiong (parts are parts by weight, and the following examples are parts by weight)
[0093]Add 10 times the amount of water to decoct Chinese weed grass, hawthorn leaves, and Panax notoginseng 3 times, each time for 1 hour, filter, combine the filtrate, concentrate under reduced pressure to a relative density of 1.10, add ethanol to make the alcohol content reach 65%, stir evenly, Stand still for 12 hours, filter with suction, recover ethanol from the filtrate under reduced pressure and concentrate to a relative density of 1.07, add an appropriate amount of water to dilute, use a macroporous adsorption resin column with an upper diameter to height ratio of 1:10, and an adsorption flow rate of 2BV·h -1 , discard the breakthrough solution, wash with 1BV water, flow rate 2BV·h -1 , discard the water washing solution, and then eluted with 3BV70% ethanol at a flow ra...
Embodiment 2
[0096] Mix the extract mixture of Orientia radiata, hawthorn leaves, Panax notoginseng and Rhizoma Chuanxiong obtained in Example 1, and prepare an injection by using conventional techniques of pharmacy.
Embodiment 3
[0098] 6 parts of Chinese weed, 5 parts of hawthorn leaves, 4 parts of Panax notoginseng and 3 parts of Chuanxiong
[0099] Add 10 times the amount of water to decoct the weed grass and hawthorn leaves 3 times, 1 hour each time, filter, combine the filtrate, concentrate under reduced pressure to a relative density of 1.10, add ethanol to make the alcohol content reach 65%, stir evenly, and let stand for 12 hour, suction filtration, the filtrate decompressed to recover ethanol and concentrate to a relative density of 1.07, add appropriate amount of water to dilute, the upper diameter height ratio of 1:10 macroporous adsorption resin column, adsorption flow rate 2BV h -1 , discard the breakthrough solution, wash with 1BV water, flow rate 2BV·h -1 , discard the water washing solution, and then eluted with 3BV70% ethanol at a flow rate of 2BV·h -1 , collecting the eluate, recovering ethanol, concentrating into a thick paste, spray-drying the residue, and pulverizing into a fine p...
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