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Method and device for testing oxygen permeation of cornea repair material

A technology for repairing materials and testing methods, which is applied in the directions of measuring devices, material separation, and analysis of materials, etc., can solve the problems of single test object of the corneal repair material oxygen permeability testing device, and achieve the effect of low maintenance frequency and lower operating costs.

Inactive Publication Date: 2010-09-15
SOUTH CHINA UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to solve the problem that the test object of the current corneal repair material oxygen permeability test device is single, and to provide a device with a simple structure that can test soft contact lenses, hard contact lenses, artificial corneas and other corneal repair materials with the same device. Oxygen Permeability Corneal Restoration Material Oxygen Permeability Testing Method and Device

Method used

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  • Method and device for testing oxygen permeation of cornea repair material
  • Method and device for testing oxygen permeation of cornea repair material
  • Method and device for testing oxygen permeation of cornea repair material

Examples

Experimental program
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Embodiment 1

[0032] The implementation steps of the testing method of the present invention are:

[0033] (1) Enter the volume V into the gas chromatograph 1 of oxygen, get the peak area S from the spectrum 1 ;

[0034] (2) The two sides of the sample to be tested are respectively passed oxygen and carrier gas, and the oxygen penetrates through the area where the sample is exposed to the oxygen flow to the side of the carrier gas, and the volume V 2 The mixed gas of oxygen and carrier gas is sent to the gas chromatograph, the amount of oxygen in the mixed gas is detected, and the peak area S is obtained from the spectrum. 2 ;

[0035] (3) The oxygen permeability coefficient Dk and oxygen permeability Dk / t of the sample can be calculated by the following formula:

[0036] Dk=(V 1 ×S 2 ×t×Q) / (S 1 ×A×p×V 2 )

[0037] Dk / t=(V 1 ×S 2 ×Q) / (S 1 ×A×p×V 2 )

[0038] Among them, Dk is the oxygen permeability coefficient, the unit is ml cm cm -2 ·s -1 ·Pa -1 ; Dk / t is the oxygen perm...

Embodiment 2

[0041] Such as figure 1 and 2 As shown, the butt joint of the oxygen cavity 21 and the cavity wall of the carrier gas cavity 24 is a matching arc surface, and the sample with a fixed shape is an arc surface. The contact lens oxygen permeability testing device in the present invention mainly includes a sample holder 20, an oxygen inlet Gas device, carrier gas inlet device and detection device, described sample holder 20 is made up of oxygen chamber 21 and carrier gas chamber 24; Oxygen chamber outlet pipeline 8; carrier gas chamber 24 is connected with carrier gas inlet device through carrier gas chamber inlet pipe 15, and is connected with detection device through carrier gas chamber outlet pipe 16; described detection device includes quantitative sampling device 17 and Gas Chromatograph19.

[0042] The oxygen intake device includes an oxygen flowmeter 6, an oxygen pipeline III5, an oxygen flow regulating valve 4, an oxygen pipeline I1 and an oxygen cylinder connected in seq...

Embodiment 3

[0052] In the present embodiment, the sample tested is an artificial cornea, using such as image 3 The sample holder, the butt joint of the oxygen chamber 21 and the carrier gas chamber 24 is a plane. The rest are the same as in Embodiment 2 and will not be repeated here.

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Abstract

The invention relates to a method and a device for testing the oxygen permeation of a cornea repair material. A sample is placed in a sample clamp; oxygen and carrier gas are introduced to two sides of the sample; and the oxygen passes through the sample and is taken to a detection device by the carrier gas for detecting the concentration of the oxygen. The test device comprises the sample clamp which consists of an oxygen cavity and a carrier gas cavity; an inlet end of the oxygen cavity is communicated with the oxygen through an inlet pipeline of the oxygen cavity; an outlet end of the oxygen cavity is evacuated through an outlet pipeline of the oxygen cavity; and an inlet end of the carrier gas cavity is communicated with the carrier gas through an inlet pipeline of the carrier gas cavity, and an outlet end of the carrier gas cavity is communicated with the detection device through an outlet pipeline of the carrier gas cavity. Compared with a coulomb sensor, a gas chromatograph used by the invention has lower price, lower repair and maintenance frequency and longer service cycle, and the operation cost is obviously reduced.

Description

technical field [0001] The invention relates to a method and device for testing the oxygen permeability of corneal repair materials, in particular, the same device can be used to test the oxygen permeability of soft contact lenses, hard contact lenses, artificial corneas and other corneal repair materials. Background technique [0002] Oxygen permeability is an important indicator of the performance of corneal repair materials, and oxygen permeability detection is an important part of the characterization of corneal repair materials. [0003] Corresponding to different types of corneal repair materials, the detection of oxygen permeability is also different: for soft contact lenses and artificial corneas, the polarographic method is generally used, and the sample is attached to the electrode. An electrochemical reaction occurs on the two poles of the electrode, and the amount of oxygen can be obtained by detecting the generated current and calculating; for rigid contact lens...

Claims

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Application Information

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IPC IPC(8): G01N30/02
Inventor 任力王迎军王家鸣赵连娜
Owner SOUTH CHINA UNIV OF TECH
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