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New application of green tea polyphenol

A technology for green tea polyphenols and uses is applied in the new use field of green tea polyphenols to achieve the effects of preventing and treating psychological stress injury, reducing the number of erections, and improving the ability of space exploration

Inactive Publication Date: 2010-07-14
INST OF HYGIENE & ENVIRONMENTAL MEDICINE PLA ACAD OF MILITARY MEDICAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Green tea polyphenols have been used in the prevention and treatment of malignant tumors and other diseases. However, there are few studies on the effect of green tea polyphenols on psychological stress injury. If drugs or functional foods containing green tea polyphenols can be developed to prevent psychological stress reduce the harm of psychological stress injury, which is economical and practical, and will greatly promote the health care industry in our country

Method used

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  • New application of green tea polyphenol
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  • New application of green tea polyphenol

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Experimental study on the prevention and / or treatment of psychological stress injury by green tea polyphenols

[0020] 1. Materials and methods

[0021] In this experiment, 50 clean-grade male Wistar rats, weighing 140-160g, were provided by the Animal Center of the Academy of Military Medical Sciences. They were raised in an SPF-grade animal room. The temperature of the animal room was controlled at (24±1)°C, and the humidity was 50%-70%. , The light-dark cycle is 12h:12h. The green tea polyphenols used in the experiment were purchased from Zhejiang Yixin Pharmaceutical Co., Ltd., batch number: GT-061201, and the purity of green tea polyphenols was 99.92%.

[0022] The experimental animals were randomly divided into 5 groups after being adapted to feeding for 1 week: normal control group, stress control group, low, medium and high doses of GTPs (green tea polyphenols) intervention stress group, in which the animals in the normal control group and stress control group ...

Embodiment 2

[0045] Take 2 g of green tea polyphenols, add 8 g of dextrin and mix well, then add appropriate amount of food coloring, put into No. 2 capsules to obtain green tea polyphenols capsules.

Embodiment 3

[0047] Take 4 g of green tea polyphenols, add 6 g of galactose and mix well, then add an appropriate amount of magnesium stearate, and press into tablets to obtain green tea polyphenol tablets.

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Abstract

The invention provides new application of green tea polyphenol in preventing and treating psychological stress injuries, which further shows that the green tea polyphenol has application in preparing medicaments or foods for preventing and treating symptoms or diseases correlative with the psychological stress injuries. The green tea polyphenol can improve the prolongation of latency and the reduction of grill-passing times and erection times of a Wistar rat in an open field test in a psychological stress state; the latency is prolonged and the number of electric shocks is increased in a step-through test; and the performance that the time for finishing a water maze and the number of errors are obviously increased is abnormal, which shows that the green tea polyphenol can improve the space exploration capacity, the cognitive function and the learning and memory ability of a psychological stress animal, has the effect of preventing and treating the psychological stress injuries, and is hopeful to be used for preparing the medicaments or the foods for preventing and treating the symptoms or the diseases correlative with the psychological stress injuries.

Description

technical field [0001] The invention relates to a new application of green tea polyphenols. Background technique [0002] Psychological stress, also known as psychosocial stress, refers to the comprehensive response state of the body caused by some natural, social or personal events acting on the human psychological process, including mental, neuroendocrine and The response of the immune system, etc. Modern society is a society of high psychological stress. People's habitual rhythm of life is disrupted, work and employment pressures increase, interpersonal relationships become increasingly complex, and natural disasters and casualty accidents occur frequently. These factors have caused panic among people. Many studies have shown that psychological stress is closely related to the occurrence and development of many organic diseases, such as cardiovascular diseases, immune system diseases and gastrointestinal diseases. Epidemiological studies have shown that people who have ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/353A61P25/00A61P9/12A61P3/10A61P9/10A61P35/00A61P25/18A61P37/08A23L1/29A23L33/00
Inventor 陈伟强赵小玲王冬兰李树田程义勇侯玥洪燕
Owner INST OF HYGIENE & ENVIRONMENTAL MEDICINE PLA ACAD OF MILITARY MEDICAL
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