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Purpose of montmorillonite in treating allergic rhinitis and skin allergy

A technology for allergic rhinitis and skin allergies, which is applied in the field of medicine and can solve problems such as high cost, large side effects, and liver damage

Inactive Publication Date: 2010-07-07
郭进军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

2. Hormone therapy. Oral hormone therapy is also commonly used in hospitals. It is very effective in treating allergic diseases, but the side effects are too large to be used frequently. It can only be temporarily controlled when the condition is severe. Commonly used hormones can seriously damage the liver and kidneys, etc. internal organs
3. Desensitization treatment, the allergens that cause allergic rhinitis are made into extracts, which are gradually increased from small doses to large doses and injected repeatedly. This method enhances the patient's ability to adapt to allergens. The disadvantage is that the course of treatment is long and the cost is high. , the effective rate is only about 30%

Method used

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  • Purpose of montmorillonite in treating allergic rhinitis and skin allergy
  • Purpose of montmorillonite in treating allergic rhinitis and skin allergy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0099] Recipe composition:

[0100] Montmorillonite 20g

[0101] Carbomer 10g

[0102] Ethyl p-hydroxybenzoate 0.3g

[0103] peppermint oil 1ml

[0104] Sodium bicarbonate 0.5g

[0105] Add deionized water to 1000ml

[0106] Preparation steps:

[0107] Accurately weigh 10g of carbomer, disperse it in about 600ml of pure water and swell for 24 hours, then add sodium bicarbonate to adjust the pH value to 4.0-5.0. In addition, dissolve 0.3g of ethyl p-hydroxybenzoate, 1ml of peppermint oil, and 20g of montmorillonite in an appropriate amount of warm pure water, and slowly add it to the upper liquid, add deionized water to 1000ml, and stir well to obtain an opaque montmorillonite gel. Glue I.

Embodiment 2

[0109] Montmorillonite 40g

[0110] Cross-linked sodium polyacrylate 400 10g

[0111] Ethyl p-hydroxybenzoate 0.3g

[0112] peppermint oil 1ml

[0113] Add deionized water to 1000g

[0114] Preparation steps:

[0115] Take 600ml of deionized water at 60°C, sprinkle cross-linked sodium polyacrylate 400 on the liquid surface, and let it swell for 24 hours to form a gel. In addition, dissolve 0.3g of ethyl p-hydroxybenzoate, 1ml of peppermint oil, and 20g of montmorillonite in an appropriate amount of warm pure water, and slowly add it to the upper liquid, add deionized water to 1000ml, and stir well to obtain an opaque montmorillonite gel. Glue II.

Embodiment 3

[0117] Recipe composition:

[0118] Montmorillonite 20g

[0119] Sodium Carboxymethyl Cellulose 30g

[0120] Ethyl p-hydroxybenzoate 0.3g

[0121] peppermint oil 1ml

[0122] Add deionized water to 1000g

[0123] Preparation steps:

[0124] Take sodium carboxymethyl cellulose, add an appropriate amount of deionized water, stir and place, let the sodium carboxymethyl cellulose fully swell, and stir well to form a gel. Separately take ethyl p-hydroxybenzoate, peppermint oil, and montmorillonite in an appropriate amount of hot deionized water, place it, cool to room temperature, mix with the above gel and stir well, and finally add water to a sufficient amount, and stir well to obtain opaque montmorillonite Gel III.

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Abstract

The invention relates to a configuration method of water solubility gel or paste containing montmorillonite, a purpose in preventing and treating allergic rhinitis (including perennial rhinitis and seasonal rhinitis) through local nasal cavity outer side (nose wing and nose bridge) administration and a purpose in treating skin allergy through the local administration of allergic skin infected part.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to the use of montmorillonite (micron-level, nano-level and mixed in different proportions between micron-level and nano-level) and montmorillonite composition, especially in the treatment of allergic diseases, especially allergic rhinitis and skin allergies aspects of use. Background technique [0002] 1. Knowledge of montmorillonite [0003] Montmorillonite is a kind of bentonite mineral. As a medicinal mineral, it was first recorded in "Compendium of Materia Medica". Nature and flavor are sweet, warm. Montmorillonite is the main component of bentonite minerals. It is named montmorillonite in the Western world because it was discovered in Montmorillon, France in 1847. Montmorillonite powder, as an efficient mucosal protective agent, an adsorbent for bacteria, viruses and their toxins, is used to treat various acute and chronic diarrhea diseases. It is highly efficient and non-toxic. List...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/06A61P11/02A61P17/00A61P37/08
Inventor 郭进军
Owner 郭进军
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