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Convection-enhanced delivery catheter with removable stiffening member

A technology for strengthening components and catheters, applied in catheters, medical devices, medical science, etc., can solve problems that affect success

Inactive Publication Date: 2012-10-10
MEDGENESIS THERAPEUTIX INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] A variety of factors are believed to significantly affect the success of local drug delivery by CED

Method used

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  • Convection-enhanced delivery catheter with removable stiffening member
  • Convection-enhanced delivery catheter with removable stiffening member
  • Convection-enhanced delivery catheter with removable stiffening member

Examples

Experimental program
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Effect test

Embodiment Construction

[0020] The catheter of the present invention is intended to be temporarily or permanently implanted in the mammalian body, preferably the brain, as a dedicated CED catheter. An embodiment of the catheter system 21 of the present invention, in figure 1 shown in , includes a catheter 22 having a main tube 23 or first elongated tubular member, within a lumen 26 of the main catheter (preferably an elongated central lumen or channel) leading a microinfusion tube 24 or a second elongated tubing. Long tubular member. Microinfusion tubing 24 is also provided with a central lumen or channel 27 . The main tube 23 has a distal end 28 with at least one end wall 29 which is preferably planar and extends perpendicularly to the longitudinal axis of the main tube. The distal end 31 of the microinfusion tube extends through the main tube, and is preferably concentrically disposed with respect to the main tube, and the inner diameter of the central lumen 26 of the main tube 23 is wider or lar...

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PUM

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Abstract

A catheter for delivering an agent to targeted tissue of a mammalian body including a first elongate tubular member having a proximal opening and a distal end wall. A second elongate tubular member having a portion extends through first elongate tubular member and has a distal end extending beyond the end wall. The first and second tubular members form an annular cavity within the first tubular member. A stiffening member has at least a portion disposed within the annular cavity for facilitating accurate placement of the distal end relative to the targeted tissue in the mammalian body and is removeable from the annular cavity after such placement without removal of the second elongate tubular member from the mammalian body. A method is provided.

Description

technical field [0001] The present invention relates to a catheter, and more particularly to a transmission-enhanced delivery catheter. Background technique [0002] Conveyance-enhanced delivery (CED) is a local delivery technique for dispensing components for infusion. CED utilizes bulk flow to deliver small or large molecules to a target site, such as the brain, through radiographic stereotaxic catheters. Bypassing the blood-brain barrier, CED can expose tumors and other target tissues to therapeutic agents, minimizing systemic exposure, resulting in fewer systemic effects. [0003] A variety of factors are believed to significantly affect the success of local drug delivery by CED. The first such factor is backflow along the outer surface of the infusion catheter, which generally occurs at larger tubing diameters and higher infusion rates. A second such factor is air intrusion and pressure spikes that can occur when the system is disconnected or reconnected after the ca...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M25/01
CPCA61M2210/0693A61M25/0068A61M2025/0188A61M2025/0063A61M2025/0004A61M2025/0042A61M25/0102A61D1/02A61D7/00A61M25/01A61M31/00
Inventor A·格兰M·卢茨
Owner MEDGENESIS THERAPEUTIX INC
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