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Chinese medicinal composition containing Chinese yams, and application thereof

A technology of composition and yam, which is applied in the direction of drug combination, medical preparations containing active ingredients, and pharmaceutical formulas, can solve the problems of drug resistance and side effects, affect the patient's physique, and inaccurate curative effect, and achieve the purpose of regulating the gastrointestinal tract. Hormone levels and immune function, improve the ability to scavenge oxygen free radicals, and improve the effect of the body's stress ability

Inactive Publication Date: 2010-06-02
ZHEJIANG CHINESE MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although FD does not endanger human life, it seriously affects people's study, work and quality of life, and takes up quite high medical expenses.
Although the prognosis of this disease is relatively good, long-term indigestion will affect the patient's physique, resulting in a decline in immunity, a sub-healthy state, and easy infection of other diseases. Therefore, this disease has gradually become a major medical care problem in modern society.
In addition, because the pathogenesis of FD has not been fully elucidated, there is no specific drug for its treatment. Western medicine is mostly limited to symptomatic treatment, with uncertain curative effects and prone to drug resistance and side effects; although traditional Chinese medicine decoctions have good curative effects, they are mostly individualized The treatment plan is not easy to promote

Method used

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  • Chinese medicinal composition containing Chinese yams, and application thereof
  • Chinese medicinal composition containing Chinese yams, and application thereof
  • Chinese medicinal composition containing Chinese yams, and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1: the preparation of the Chinese medicine combination extract containing Chinese yam

[0021] 1. Prescription

[0022] Yam 100g

[0023] Job's tears 100g

[0024] Tangerine peel 50g

[0025] 2. Preparation method

[0026] Take the above prescription medicinal materials, add water to extract twice, add 3 times the amount of water for the first time, soak for 0.5 hours, extract for 1.5 hours, add 1.5 times the amount of water for the second time, extract for 1 hour, combine the decoction, filter, and decompress the filtrate Concentrate to the clear paste of 0.8g / ml, get the clear paste, stir and add 95% (v / v) ethanol, make the final concentration of ethanol be 65% (v / v), leave standstill for 24 hours, get the supernatant, filter The ethanol was recovered from the filtrate under reduced pressure and concentrated to a crude drug content of 12.5 g per milliliter.

Embodiment 2

[0028] 1. Prescription

[0029] Yam 105g

[0030] Job's tears 105g

[0031] Chenpi 40g

[0032] 2. Preparation method

[0033] Take the above prescription medicinal materials, add water to extract twice, add 3 times the amount of water for the first time, soak for 0.5 hours, extract for 1.5 hours, add 1.5 times the amount of water for the second time, extract for 1 hour, combine the decoction, filter, and decompress the filtrate Concentrate to the clear paste of 0.9g / ml, get the clear paste, stir and add 95% (v / v) ethanol, make the final concentration of ethanol be 70% (v / v), leave standstill for 24 hours, get the supernatant, filter The ethanol was recovered from the filtrate under reduced pressure and concentrated to a crude drug content of 12.5 g per milliliter.

Embodiment 3

[0035] 1. Prescription

[0036] Yam 100g

[0037] Job's tears 95g

[0038] Tangerine peel 55g

[0039] 2. Preparation method

[0040] Take the above prescription medicinal materials, add water to extract twice, add 2 times the amount of water for the first time, soak for 1 hour, extract for 2 hours, add 1.5 times the amount of water for the second time, extract for 1 hour, combine the decoction, filter, and decompress the filtrate Concentrate to the clear paste of 0.8g / ml, get the clear paste, stir and add 90% (v / v) ethanol, make the final concentration of ethanol be 60% (v / v), leave standstill for 24 hours, get the supernatant, filter The ethanol was recovered from the filtrate under reduced pressure and concentrated to a crude drug content of 12.5 g per milliliter.

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Abstract

The invention provides a Chinese medicinal composition containing Chinese yams. The composition consists of the following components in mass ratio: 5 to 25 parts of Chinese yams, 5 to 25 parts of coix seeds and 1 to 15 parts of tangerine peel. The Chinese medicinal composition containing Chinese yams has the main advantages of: (1) reasonable formulation, function of invigorating spleen and regulating qi and capability of effectively regulating astrointestinal motor function; (2) capability of improving stress ability of organisms; (3) capability of regulating hormone level and immune function of stomachs-intestines with functional dyspepsia; and (4) capability of improving the ability of the organisms to clear oxygen free radicals.

Description

(1) Technical field [0001] The invention relates to a traditional Chinese medicine composition containing yam and its application in the preparation of medicines for preventing and treating functional dyspepsia. (2) Background technology [0002] Functional Dyspepsia (FD) refers to patients with postprandial fullness discomfort, early satiety, belching, nausea, vomiting, upper abdominal pain or burning sensation in the upper abdomen, and the organic diseases that cause these symptoms are excluded after examination. A group of clinical syndromes that Rome III criteria divide into postprandial discomfort syndrome and epigastric pain syndrome. Its incidence is very common, and almost everyone has symptoms of indigestion in their lifetime. Epidemiological studies in western countries have shown that 15% to 20% of people experience indigestion every year, and domestic statistics account for 18.9% of the normal population, about 40% of the number of gastroenterology patients, and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61K9/14A61K9/16A61K9/20A61K9/48A61P1/14
Inventor 徐珊朱飞叶张永生杨季国
Owner ZHEJIANG CHINESE MEDICAL UNIVERSITY
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