Orthopedic internal fixation plate and preparation method thereof
A fixed plate and orthopedic technology, applied in the field of medical materials, can solve the problems of increasing patient pain, affecting recovery effect, prone to displacement, slippage, etc., to achieve pain relief, good biocompatibility and wear resistance, and prevent adhesion Effect
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[0026] The preparation method of the orthopedic internal fixation plate provided by the invention comprises:
[0027] a) Make the mold of the orthopedic internal fixation plate, so that the cross-section of the side of the produced orthopedic internal fixation plate in contact with the spine is an arc that matches the spine. For details, please refer to figure 1 .
[0028] b) Put the biodegradable polymer material into the mould, and perform compression molding. The biodegradable polymer material is preferably PLLA or a mixture of PLLA and HA, and the weight ratio of PLLA to HA in the mixture of PLLA and HA is preferably 8:1˜11:1.
[0029] Preferably, before putting the above biodegradable polymer materials into the mould, it also includes heating PLLA or the mixture of PLLA and HA to 180°C to 200°C and stirring and mixing evenly, because the PLLA used in the preparation process Organic solvents, so there will always be residual solvents in the finished PLLA, which can be re...
Embodiment 1
[0032] First prepare the mold. Then the PLLA was heated to 180°C in a torque rheometer and stirred evenly. Take out the PLLA and put it into the mold, mold it at 190°C and 9.5MPa for 2.5min, then cool down to 120°C, keep it warm for 1.5min, then cool down to room temperature and take out the molded fixing plate. After testing, the impact strength of the obtained orthopedic internal fixation plate is 7.8±0.94KJ / m 2 . The orthopedic internal fixation plate was transplanted into animals for experiments, and the impact strength after 7 months of transplantation was 6.99±1.42KJ / m 2 .
Embodiment 2
[0034] First prepare the mold. Then, PLLA and HA with a weight ratio of 9:1 were heated to 190° C. in a torque rheometer and stirred and mixed. Take out the mixture of PLLA and HA and put it into a mold, mold it at 195°C and 10MPa for 2min, then cool down to 118°C, keep it warm for 1min, then cool down to room temperature and take out the molded fixing plate.
[0035] After testing, the impact strength of the obtained orthopedic internal fixation plate is 7.46±0.4KJ / m 2 . The orthopedic internal fixation plate was transplanted into animals for experiments, and the impact strength after 7 months of transplantation was 14.75±0.9KJ / m 2 .
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