Production technology of grape pip and grape skin extract

Abstract

The invention relates to a production technology of grape pip and grape skin extract, belonging to the technical field of plant extract. The production technology comprises the following steps: adding the raw materials of grape pip and grape skin into 50-70% of alcohol the volume of which is eight times of the raw materials; extracting the grape pip and grape skin at the extracting temperature of 70 DEG C for three times; collecting the extraction solution, vacuum evaporating, recovering the alcohol and collecting supernate after centrifugation; carrying out chromatographic column on the centrifuged extraction solution in macroporous resin with the diameter height ratio of 1:10; eluting with 5-15% of alcohol in batch until the eluate is clear; desorbing with 70% of alcohol, collecting the desorption solution after desorption; carrying out chromatographic column on the centrifuged extraction solution in macroporous resin with the diameter height ratio of 1:10; collecting the desorption solution, decompressing and recovering the alcohol, concentrating into thick paste, and vacuum drying to obtain the grape pip and grape skin extract. The production technology of the invention adopts multi-time extraction, multistage centrifugation and two-time desorption method of crude extract and fine extract, thus greatly improving the content of effective components.

Description

technical field [0001] The invention relates to a production process of grape seed and skin extract, which belongs to the technical field of plant extraction. Background technique [0002] At present, grape seed and skin extracts, as a natural radical scavenger and antioxidant, are more and more popular due to their anti-aging, anti-tumor, anti-cancer and prevention of cardiovascular diseases and arteriosclerosis. At present, the active ingredients extracted from grape seeds and skins are mainly polyphenols, mainly catechins, and catechins or epicatechins are used as units to form dimers, Proanthocyanidins composed of oligomers such as trimers, and the medicinal value of oligomeric proanthocyanidins are more and more recognized by people. At present, the extraction methods for grape seeds and skins mainly include the following: 1. Solvent 2, precipitation method; 3, adsorption column chromatography etc., but adopt the above-mentioned method to extract the active ingredient ...

AI Technical Summary

Problems solved by technology

[0002] At present, grape seed and skin extracts, as a natural radical scavenger and antioxidant, are more and more popular due to their anti-aging, anti-tumor, anti-cancer and prevention of cardiovascular diseases and arteriosclerosis. At present, the active ingredients extracted from grape seeds and skins are mainly polyphenols, mainly catechins, and catechins or epicatechins are used as units to form dimers, Proanthocyanidins composed of oligomers such as trimers, and the medicinal value of oligomeric proanthocyanidins are more and more recognized by people. At present, the extraction methods for grape seeds and skins mainly include the following: 1. Solvent 2, precipitation method; 3, adsorption column chromatography etc., but adopt the above-mentioned method to extract the active ingredient of grape seed, skin leaf, all there is a shortcoming, be exactly at present owing to being subjected to the influence of climate and collection time, currently grape seed, The quality of the skin leaves is not high, and the content of active ingredients in the raw grape seeds and skin leaves used for extraction is getting lower and lower. Not high, resulting in greatly reduced quality and value of grape seed and skin extracts

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