Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Pharmaceutical composition for treating ulcerative colitis and preparation method thereof

A technology of ulcerative colitis and composition, applied in the field of traditional Chinese medicine, can solve problems such as multiple side effects

Inactive Publication Date: 2011-11-23
SUN YAT SEN UNIV
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the main drugs for treating UC in Western medicine are amino acid salicylic acid, corticosteroids, immunosuppressants, etc. The initial effect of these drugs is acceptable, but there are many side effects in long-term use

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Pharmaceutical composition for treating ulcerative colitis and preparation method thereof
  • Pharmaceutical composition for treating ulcerative colitis and preparation method thereof
  • Pharmaceutical composition for treating ulcerative colitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1: The pharmaceutical composition of the present invention is mainly made of the following crude drugs in parts by weight, 5-15 parts of Coptis Rhizoma and 5-15 parts of Atractylodes Rhizome.

[0025] a) Weigh Coptidis Rhizome and Atractylodes Rhizome respectively according to the weight ratio of 5-15:5-15;

[0026] b) Coptidis rhizome is extracted by ethanol reflux to form extract powder; cinnamon extracts volatile oil; Atractylodis extracts volatile oil, then water extracts to form extract powder;

[0027] c) mixing the volatile oil with the extract powder, adding auxiliary materials, and processing it into an oral dosage form.

[0028] For example: it can be processed into granules (infusions), tablets (plain tablets, coated tablets, dispersible tablets, fast-disintegrating tablets, effervescent tablets, etc.), capsules (hard capsules, soft capsules), and oral liquids.

Embodiment 2

[0030] Weigh Coptidis Rhizome and Atractylodes Rhizome respectively according to the weight ratio of 10:15, and the remaining steps are the same as in Example 1 to obtain the present invention (pharmaceutical composition).

Embodiment 3

[0032] Weigh Coptidis Rhizome and Atractylodes Rhizome respectively according to the weight ratio of 10:10, and the remaining steps are the same as in Example 1 to obtain the present invention (pharmaceutical composition).

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a pharmaceutical composition for treating ulcerative colitis and a preparation method thereof. The pharmaceutical composition is mainly prepared by the following raw medicines based on parts by weight: 5-15 parts of rhizoma coptidis and 5-15 parts of rhizoma atractylodis. The preparation method of the medicine comprises the following steps: (a) respectively weighing the rhizoma coptidis and the rhizoma atractylodis according to a certain weight proportion for standby; (b) extracting the rhizoma coptidis by refluent ethanol so as to form extract powder; extracting volatile oil of the rhizoma atractylodis and then extracting residues by water to form extract powder; (c) mixing the volatile oil and the extract powder and adding an auxiliary material to be processed to form an oral formulation. The medicine has the effects of temporary treatment by cleaning heat and drying humidity and permanent treatment by strengthening the spleen and tonifying and has the obvious effect on treating chronic ulcerative colitis.

Description

[technical field] [0001] The invention relates to a pharmaceutical composition for treating ulcerative colitis and a preparation method of the pharmaceutical composition, belonging to the field of traditional Chinese medicine. [Background technique] [0002] Ulcerative colitis (ulcerative colitis, UC) is also called chronic nonspecific colitis (referred to as ulcerative colitis). Organizations are listed as one of the intractable diseases. The disease occurs all over the world. Existing research data show that its epidemiological characteristics are greatly affected by regions, races, ages, etc. The incidence rates in Northern Europe, Western Europe, and North America are higher than those in other regions of the world. Between / 100,000 and 12 / 100,000, another research report from Israel pointed out that the incidence rate is as high as 167 / 100,000, and it can occur at any age, and it is more common in 20-40 years old, accounting for about 70%, male and female. rate did no...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/718A61P1/00A61P1/04
Inventor 黄河清刘培庆宁海蓉黄文革陈凤英郭芬芬刘慰华
Owner SUN YAT SEN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com