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Chinese medicine composition used for treating non-active stage infiltrative exophthalmos of thyroid-associated ophthalmopathy and preparation method thereof

An inactive, invasive technology, applied in the direction of drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as lack of system integrity

Active Publication Date: 2009-09-16
LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although all have achieved certain curative effects, they have more one-sided limitations and lack of system integrity

Method used

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  • Chinese medicine composition used for treating non-active stage infiltrative exophthalmos of thyroid-associated ophthalmopathy and preparation method thereof
  • Chinese medicine composition used for treating non-active stage infiltrative exophthalmos of thyroid-associated ophthalmopathy and preparation method thereof
  • Chinese medicine composition used for treating non-active stage infiltrative exophthalmos of thyroid-associated ophthalmopathy and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Weigh 1000 grams of raw Astragalus membranaceus, 1000 grams of Salvia miltiorrhiza, 1000 grams of white mustard seed, 1500 grams of plantain seed, 1500 grams of Hedyotis diffusa, 900 grams of cassia twig, add 4 times the amount of water, decoct for 1.5 hours, filter, and concentrate To a clear paste with a relative density of about 1.35 (80°C), add an appropriate amount of dextrin, granulate (14-16 mesh), vacuum dry (80°C), and pack.

Embodiment 2

[0027] Weigh 1000 grams of raw Astragalus membranaceus, 2000 grams of Salvia miltiorrhiza, 1500 grams of white mustard seed, 2000 grams of plantain seed, 2000 grams of Hedyotis diffusa, 1200 grams of cassia twig, add 6 times the amount of 75% ethanol, and reflux extraction twice, each time After 1.5 hours, filter, combine the filtrates, recover ethanol until there is no alcohol smell, concentrate to a clear paste with a relative density of about 1.35 (80°C), add an appropriate amount of dextrin, granulate (14-16 mesh), and vacuum dry (80°C) , subpackage.

Embodiment 3

[0029] Weigh 1,000 grams of raw Astragalus membranaceus, 3,000 grams of Salvia miltiorrhiza, 1,500 grams of white mustard seed, 3,000 grams of plantain seed, 3,000 grams of Hedyotis diffusa, 1,500 grams of cassia twig, add 8 times the amount of 90% ethanol, and reflux three times for 1.5 hours each time , filter, combine the filtrates, recover ethanol until there is no alcohol smell, concentrate to a clear paste with a relative density of about 1.35 (80°C), add an appropriate amount of dextrin, granulate (14-16 mesh), vacuum dry (80°C), and separate Pack.

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Abstract

The invention discloses a Chinese medicine composition used for treating non-active stage infiltrative exophthalmos of thyroid-associated ophthalmopathy; the traditional Chinese medicine composition is prepared by the following bulk drugs by weight: 10 parts to 30 parts of raw astragalus root, 10 parts to 30 parts of salvia, 9 parts to 15 parts of white mustard Seed, 15 parts to 30 parts of asiatic plantain seed, 15 parts to 30 parts of hedyotis diffusa, and 9 parts to 15 parts of cassia twig. The clinical study in treating non-active stage infiltrative exophthalmos of thyroid-associated ophthalmopathy shows that the total effective rate of the Chinese medicine syndrome score curative effect of the Chinese medicine composition is 85.29 percent; and the Chinese medicine composition can effectively reduce the exophthalmos degree of the patients with non-active stage infiltrative exophthalmos of thyroid-associated ophthalmopathy, and the total effective rate is 76.47 percent. The invention also discloses a preparation method of traditional Chinese medicine composition granules.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating thyroid-associated ophthalmopathy (infiltrating exophthalmos in inactive stage); the invention also relates to a preparation method of the traditional Chinese medicine composition. Background technique [0002] In recent years, due to environmental factors such as genetic factors, increased intake of iodized salt, tense pace of life, and increased work pressure, the incidence of thyroid-related ophthalmopathy has increased year by year. Therefore, among the orbital diseases of the adult group, thyroid-related ophthalmopathy ranks first at home and abroad. bit. [0003] Scholars at home and abroad have a long history of research on thyroid-related ophthalmopathy, but the progress is slow. In the past 20 years, with the rapid development of science and technology, the research process of thyroid-associated ophthalmopathy has been greatly promoted, and the close relationship...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61P27/02A61P5/16
Inventor 李红徐蓉娟
Owner LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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