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Water for preparing dialysate and dialysate and method of producing dialysate using the same, and dialyzer

A solution and water technology, applied in dialysis systems, water/sewage treatment, chemical instruments and methods, etc., can solve problems such as insufficient strategies and infeasibility, and achieve the effect of preventing adverse effects

Active Publication Date: 2009-09-02
NIKHON TRIM KO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, conventional strategies are still not enough
Complete inhibition of glucose degradation products is not technically feasible at this stage

Method used

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  • Water for preparing dialysate and dialysate and method of producing dialysate using the same, and dialyzer
  • Water for preparing dialysate and dialysate and method of producing dialysate using the same, and dialyzer
  • Water for preparing dialysate and dialysate and method of producing dialysate using the same, and dialyzer

Examples

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Effect test

Embodiment Construction

[0032] The water for preparing the dialysis solution of the present invention has a dissolved hydrogen concentration of 50 to 600 ppb, preferably 100 to 400 ppb, particularly preferably 100 to 150 ppb. If the concentration of dissolved hydrogen is less than 50 ppb, a dialysis solution prepared using such dialysis solution preparation water cannot sufficiently prevent adverse effects of glucose degradation products on living organisms. If the water for dialysis solution preparation includes more than 600 ppb of dissolved hydrogen, the effect of preventing adverse effects of glucose degradation products on living organisms does not increase any further. As used herein, dissolved hydrogen refers to H+, H·, H 2. The concentration of dissolved hydrogen refers to the value measured by a hydrogen dissolved meter DH-35A (product of DKK-TOA Corporation).

[0033] The water for dialysis solution preparation of the present invention has a pH of 7 to 10, preferably 8.5 to 9.5. If the p...

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Abstract

The invention provides a water for preparing a dialysate which is a water having a dissolved hydrogen concentration of from 50 to 600 ppb and a pH value of from 7 to 10 and satisfying the water quality standards as specified in ISO 13959 and to be used in preparing a dialysate by diluting a stock agent for a dialysate containing at least 50 ng / mL of glucose decomposition products; a method of preparing a dialysate by diluting a stock agent for a dialysate by using the above water; and the dialysate thus obtained. It is possible to provide a dialysate by which undesirable effects of glucose decomposition products on the living body can be inhibited, a water for preparing a dialysate to be used therefore, a method of producing a dialysate and a dialyzer can be provided by using a dialyzer having a means of supplying a water for preparing a dialysate, which is a water having a dissolved hydrogen concentration of from 50 to 600 ppb and a pH value of from 7 to 10 and satisfying the water quality standards as specified in ISO 13959, a means of storing a stock agent for a dialysate containing at least 50 ng / mL of glucose decomposition products, and a means of preparing a dialysate by diluting the stock agent for a dialysate with the water for preparing a dialysate.

Description

technical field [0001] The present invention relates to water for the preparation of dialysis solutions, dialysis solutions using such water, methods for producing dialysis solutions and dialysis equipment Background technique [0002] Dialysis is known to be an effective treatment for a patient with renal insufficiency whose kidney function has deteriorated so that he / she cannot urinate to regulate the amount of water and remove metabolic toxic substances, including body waste such as urea. Dialysis treatment is mainly divided into hemodialysis (HD) and peritoneal dialysis. Hemodialysis is a treatment method that includes the steps of introducing blood outside the body using a blood pump, directing the blood through a dialyzer (dialyzer) into contact with a dialysis solution to remove metabolic toxic substances and water by diffusion based on a concentration gradient, The purified blood is continuously returned to the body (blood). Peritoneal dialysis is a treatment metho...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M1/14C02F1/46B01D61/02
CPCA61K33/00C02F2001/4619A61K31/7004B01D61/025C02F2103/026C02F1/001C02F1/283C02F1/441A61M1/1656C02F9/00A61K45/06A61M1/1666A61K2300/00A61M1/14B01D61/02C02F1/4693C02F1/445C02F2201/002
Inventor 桦山繁森泽绅胜
Owner NIKHON TRIM KO LTD
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