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Gi and pancreatic device for treating obesity and diabetes

A pancreas, subject-based technology for the treatment of obesity and diabetes, capable of addressing disrupted fasting patterns of myoelectric activity, dose-dependent increases in pancreatic protein secretion, and dose-dependent increases

Inactive Publication Date: 2009-08-26
BETASTIM LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

CCK-OP disrupts the fasted pattern of myoelectric activity, causing a dose-dependent increase in spike potential and causing a dose-dependent increase in pancreatic protein secretion

Method used

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  • Gi and pancreatic device for treating obesity and diabetes
  • Gi and pancreatic device for treating obesity and diabetes
  • Gi and pancreatic device for treating obesity and diabetes

Examples

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Embodiment Construction

[0207] specific implementation plan

[0208] figure 1 is a schematic diagram of a system 10 for treating obesity and diabetes according to one embodiment of the present invention. System 10 generally includes control unit 20, feeding sensor 22, intragastric balloon 24, tissue stimulator 26, and pancreatic stimulator 28 implantable in pancreas 30 of a subject. In response to the detection of eating by the eating sensor 22, the control unit 20 drives the tissue stimulator 26 to stimulate the vagus nerve or the enteric nervous system (ENS) to reduce appetite, and / or drives the pancreatic stimulator 28 to stimulate pancreatic beta cells to regulate insulin production and / or Blood glucose is regulated in other ways (dotted line 31 symbolically represents the vagus nerve innervating the upper gastrointestinal tract and pancreas). It should be noted that while some embodiments of the present invention are described with respect to tissue stimulators 26 that apply stimulation to neu...

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PUM

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Abstract

The invention provides a method, including placing first and second electrodes (90) at respective first and second sites of a duodenum (40) of a subject, and activating the electrodes (90) to increase a blood insulin level of the subject. Other embodiments are also described.

Description

[0001] Cross reference to related applications [0002] This patent application is a continuation-in-part of U.S. Application 11 / 279,355, filed April 11, 2006, entitled "GI and Pancreatic Devices for the Treatment of Obesity and Diabetes" and claims the following priority: [0003] (a) U.S. Provisional Patent Application 60 / 699,442, entitled "GI and Pancreatic Devices for the Treatment of Obesity and Diabetes," filed July 13, 2005, by Alon and Gross, and [0004] (b) US Provisional Patent Application 60 / 720,951, entitled "GI and Pancreatic Devices for the Treatment of Obesity and Diabetes," filed September 26, 2005, by Alon and Gross. All of the above applications are incorporated herein by reference. technical field [0005] The present invention relates generally to treating obesity and diabetes, and in particular to methods and devices for treating obesity and diabetes in the gastrointestinal tract and pancreas. Background technique [0006] Obesity and diabetes are oft...

Claims

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Application Information

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IPC IPC(8): A61N1/18
Inventor 约西·格罗斯雅各布·贝纳里拉德温·哈瓦莱露丝·阿隆
Owner BETASTIM LTD
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