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Combination with blood sugar reducing function and preparation method thereof

A composition and a hypoglycemic technology, which are applied in the directions of medical preparations containing active ingredients, food preparation, drug combinations, etc., can solve problems such as adverse reactions, achieve the effects of no toxic and side effects, improve polydipsia, and be convenient to take

Inactive Publication Date: 2009-07-29
BEIJING INCREASEPHARM CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Now clinically, insulin therapy and oral hypoglycemic drugs are mostly used in the treatment of diabetes. However, diabetes is a life-long disease that requires long-term medication. The injection method of insulin often brings a lot of inconvenience to patients. Oral hypoglycemic drugs are mostly chemical drugs, and long-term use can also cause a series of adverse reactions

Method used

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  • Combination with blood sugar reducing function and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Preparation of capsules of the composition of the present invention

[0044] a) take by weighing fresh cactus 10kg, guava leaf 3kg, chromium gluconate 0.006kg;

[0045]b) Squeeze fresh cactus to extract juice, dry, crush to obtain cactus extract, or wash fresh cactus, cut into strips, dry, crush, soak, pretreat, ultrasonicate, filter, take filtrate, and precipitate with ethanol , centrifuge (4500r / min), get the precipitate, wash with ethanol, and freeze-dry to obtain cactus crude polysaccharide; Guava leaves are extracted with 10 times the amount and 8 times the amount of 70% ethanol under reflux, each time for 1 hour, and the extracts are combined, Filtrate, concentrate under reduced pressure, dry, and pulverize to obtain guava leaf extract;

[0046] c) Mix the above extracts evenly, add chromium gluconate, dry, and pack into hard gelatin capsules.

Embodiment 2

[0048] Preparation of granules of the composition of the present invention

[0049] a) take by weighing fresh cactus 5kg, guava leaf 1kg, chromium gluconate 0.003kg;

[0050] b) Squeeze fresh cactus to extract juice, dry, crush to obtain cactus extract, or wash fresh cactus, cut into strips, dry, crush, soak, pretreat, ultrasonicate, filter, take filtrate, and precipitate with ethanol , centrifuge (4500r / min), get the precipitate, wash with ethanol, and freeze-dry to obtain cactus crude polysaccharide; Guava leaves are extracted with 10 times the amount and 8 times the amount of 70% ethanol under reflux, each time for 1 hour, and the extracts are combined, Filtrate, concentrate under reduced pressure, dry, and pulverize to obtain guava leaf extract;

[0051] c) Mix the above extracts evenly, pulverize them into powder, add chromium gluconate, mix evenly, add ethanol as a binder, and add an appropriate amount of starch as a filler to make granules.

Embodiment 3

[0053] Preparation of granules of the composition of the present invention

[0054] a) take by weighing fresh cactus 20kg, guava leaf 10kg, chromium gluconate 0.009kg;

[0055] b) Squeeze fresh cactus to extract juice, dry, crush to obtain cactus extract, or wash fresh cactus, cut into strips, dry, crush, soak, pretreat, ultrasonicate, filter, take filtrate, and precipitate with ethanol , centrifuge (4500r / min), get the precipitate, wash with ethanol, and freeze-dry to obtain cactus crude polysaccharide; Guava leaves are extracted with 10 times the amount and 8 times the amount of 70% ethanol under reflux, each time for 1 hour, and the extracts are combined, Filtrate, concentrate under reduced pressure, dry, and pulverize to obtain guava leaf extract;

[0056] c) Mix the above extracts evenly, pulverize them into powder, add chromium gluconate, mix evenly, add ethanol as a binder, and add an appropriate amount of starch as a filler to make granules.

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PUM

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Abstract

The invention discloses a composition with the function of reducing blood sugar and a preparation method thereof. The composition is prepared from fresh cactus, guava leaf and glucose chromic acid according to certain weight proportion. The composition can be prepared into any common preparation formulation. The composition of the invention has the efficacy of reducing blood sugar, and can be used for treating diabetes.

Description

technical field [0001] The invention relates to a composition with hypoglycemic function and a preparation method thereof, belonging to the field of medicine and health food. Background technique [0002] Diabetes is a syndrome of metabolic abnormalities caused by the interaction of genetic and environmental factors. Long-term diabetes can cause chronic complications of multiple system organs, leading to dysfunction and failure, and become the main cause of disability and death. At present, the prevalence of diabetes in the Chinese population has a significant upward trend in recent years. Since the etiology and pathogenesis of diabetes are not yet fully understood, there is still a lack of effective etiological treatments. Now clinically, insulin therapy and oral hypoglycemic drugs are mostly used in the treatment of diabetes. However, diabetes is a lifelong disease that requires long-term medication. The injection method of insulin often brings a lot of inconvenience to ...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61P3/10A23L1/30A61K31/194
Inventor 邹明琛
Owner BEIJING INCREASEPHARM CORP LTD
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