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Combination with blood sugar reducing function and preparation method thereof

A composition and a hypoglycemic technology, which are applied in the directions of medical preparations, drug combinations, and pharmaceutical formulations containing active ingredients, can solve problems such as adverse reactions, and achieve the effects of no toxic side effects, definite curative effect, and low price.

Inactive Publication Date: 2009-07-29
BEIJING INCREASEPHARM CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Now clinically, insulin therapy and oral hypoglycemic drugs are mostly used in the treatment of diabetes. However, diabetes is a life-long disease that requires long-term medication. The injection method of insulin often brings a lot of inconvenience to patients. Oral hypoglycemic drugs are mostly chemical drugs, and long-term use can also cause a series of adverse reactions

Method used

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  • Combination with blood sugar reducing function and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Preparation of capsules of the composition of the present invention

[0044] a) Degrease extruded rice bran (through a 120-mesh sieve), extract with hot water, centrifuge (3000r / min, 20min), take the supernatant, add ALPHA-amylase (pH6.0, 1h), add glucoamylase ( pH4.0, 1h), centrifuge (3000r / min, 20min), take supernatant, add TCA (pH4.5), centrifuge (1200r / min, 10min), take supernatant, 75% ethanol stand overnight, Centrifuge (1200r / min, 10min), take the precipitate, and freeze-dry or spray-dry the precipitate to obtain rice bran crude polysaccharide; squeeze fresh cactus to extract juice, dry, and crush to obtain cactus extract, or fresh cactus, wash, cut Strips, drying, crushing, soaking, pretreatment, ultrasonic treatment, filtration, take the filtrate, precipitate with ethanol, centrifuge (4500r / min), take the precipitate, wash with ethanol, and freeze-dry to obtain cactus crude polysaccharide; the guava leaves Use 10 times and 8 times the amount of 70% ethanol to ...

Embodiment 2

[0047] Preparation of granules of the composition of the present invention

[0048] a) Degrease extruded rice bran (through a 120-mesh sieve), extract with hot water, centrifuge (3000r / min, 20min), take the supernatant, add ALPHA-amylase (pH6.0, 1h), add glucoamylase ( pH4.0, 1h), centrifuge (3000r / min, 20min), take supernatant, add TCA (pH4.5), centrifuge (1200r / min, 10min), take supernatant, 75% ethanol stand overnight, Centrifuge (1200r / min, 10min), take the precipitate, and freeze-dry or spray-dry the precipitate to obtain rice bran crude polysaccharide; squeeze fresh cactus to extract juice, dry, and crush to obtain cactus extract, or fresh cactus, wash, cut Strips, drying, crushing, soaking, pretreatment, ultrasonic treatment, filtration, take the filtrate, precipitate with ethanol, centrifuge (4500r / min), take the precipitate, wash with ethanol, and freeze-dry to obtain cactus crude polysaccharide; the guava leaves Use 10 times and 8 times the amount of 70% ethanol to ...

Embodiment 3

[0051] Preparation of granules of the composition of the present invention

[0052] a) Degrease extruded rice bran (through a 120-mesh sieve), extract with hot water, centrifuge (3000r / min, 20min), take the supernatant, add ALPHA-amylase (pH6.0, 1h), add glucoamylase ( pH4.0, 1h), centrifuge (3000r / min, 20min), take supernatant, add TCA (pH4.5), centrifuge (1200r / min, 10min), take supernatant, 75% ethanol stand overnight, Centrifuge (1200r / min, 10min), take the precipitate, and freeze-dry or spray-dry the precipitate to obtain rice bran crude polysaccharide; squeeze fresh cactus to extract juice, dry, and crush to obtain cactus extract, or fresh cactus, wash, cut Strips, drying, crushing, soaking, pretreatment, ultrasonic treatment, filtration, take the filtrate, precipitate with ethanol, centrifuge (4500r / min), take the precipitate, wash with ethanol, and freeze-dry to obtain cactus crude polysaccharide; the guava leaves Use 10 times and 8 times the amount of 70% ethanol to ...

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Abstract

The invention discloses a composition with the function of reducing blood sugar and a preparation method thereof. The composition is prepared from rice bran crude polyoses, cactus extract and guava leaf extract according to certain weight proportion. The composition can be prepared into any common preparation formulation. The composition of the invention has the efficacy of reducing blood sugar, and can be used for treating diabetes.

Description

technical field [0001] The invention relates to a composition with hypoglycemic function and a preparation method thereof, belonging to the field of medicine and health food. Background technique [0002] Diabetes is a syndrome of metabolic abnormalities caused by the interaction of genetic and environmental factors. Long-term diabetes can cause chronic complications of multiple system organs, leading to dysfunction and failure, and become the main cause of disability and death. At present, the prevalence of diabetes in the Chinese population has a significant upward trend in recent years. Since the etiology and pathogenesis of diabetes are not yet fully understood, there is still a lack of effective etiological treatments. Now clinically, insulin therapy and oral hypoglycemic drugs are mostly used in the treatment of diabetes. However, diabetes is a lifelong disease that requires long-term medication. The injection method of insulin often brings a lot of inconvenience to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/61A61P3/10A61K31/715C12P19/04
Inventor 邹明琛
Owner BEIJING INCREASEPHARM CORP LTD
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