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Method for pressing spirulina special-shaped tablets

A technology of spirulina and spirulina powder, which is applied in the directions of medical raw materials derived from algae, antidote, and pill transportation, can solve the problems of poor tablet friability and few tablets, and achieves qualified friability and can be used as auxiliary materials Small amount, one-sided smooth effect

Inactive Publication Date: 2009-07-22
溧阳市天目湖保健品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, spirulina is used in preparations, generally filled in capsules or bags, and less used in tablets
And if it is pressed into tablets, it can have the advantages of convenient taking and low cost. However, at present, pressing tablets according to the general process can only compress round tablets and need to add a large amount of auxiliary materials such as starch, dextrin, and microcrystalline cellulose. Large amount of starch excipients
At the same time, because the spirulina powder is relatively loose, the friability of the compressed tablet is poor, let alone compressed into a special-shaped tablet.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A. Take 20kg of spirulina powder as a load. Continuously pulverize for 30 to 40 minutes with a beili pulverizer, keep the condensed water open during the pulverization process, and pulverize to 400 mesh to obtain superfine spirulina powder;

[0030] B. Get the above-mentioned ultra-fine spirulina powder, lay it flat in a stainless steel tray, the thickness of the algae powder is 1cm, get 5% deionized water of the weight of the algae powder, and spray the deionized water evenly on the ultra-fine spirulina powder;

[0031] C. Place the spirulina powder sprayed with water in an environment of 24°C and 45% humidity for 24 hours to naturally volatilize the water; the spirulina gradually forms granules naturally;

[0032] D. put into oven again 80 ℃ and dry for 4 hours, obtain spirulina granule, measure its moisture content to be 4%~5%;

[0033] F. add the magnesium stearate of 0.1% of spirulina granule weight, directly press special-shaped tablet.

Embodiment 2

[0035] A. Take 20kg of spirulina powder as a load. Continuously pulverize for 30 to 40 minutes with a beili pulverizer, keep the condensed water open during the pulverization process, and pulverize to 200 mesh to obtain superfine spirulina powder;

[0036] B. Get the above-mentioned ultra-fine spirulina powder, spread it flat in a stainless steel tray, the thickness of the algae powder is 1.5cm, get 3% deionized water of the weight of the algae powder, and spray the deionized water evenly on the ultra-fine spirulina powder;

[0037] C. Place the spirulina powder sprayed with water in an environment of 10°C and 50% humidity for 28 hours to naturally volatilize the water; the spirulina gradually forms granules naturally;

[0038] D. put into oven again 60 ℃ and dry for 6 hours, obtain spirulina granule, measure its moisture content to be 4%~5%;

[0039] F. Add 0.05% magnesium stearate of spirulina granule weight, directly compress oval tablet.

Embodiment 3

[0041] A. Take 20kg of spirulina powder as a load. Continuously pulverize for 30 to 40 minutes with a beili pulverizer, keep the condensed water open during the pulverization process, and pulverize to 600 mesh to obtain superfine spirulina powder;

[0042] B. Get the above-mentioned ultra-fine spirulina powder, lay it flat in a stainless steel tray, the thickness of the algae powder is 0.5cm, get 8% deionized water of the weight of the algae powder, and spray the deionized water evenly to the ultra-fine spirulina powder;

[0043] C. Place the spirulina powder sprayed with water in an environment with a humidity of 65% at 20°C for 18 hours, and the water will evaporate naturally, and the spirulina will gradually form granules;

[0044] D. put into oven again 70 ℃ and dry for 5 hours, obtain spirulina granule, measure its moisture content to be 4%~5%;

[0045] F. add the magnesium stearate of 0.3% of spirulina granule weight, directly press special-shaped tablet.

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Abstract

The invention discloses a method for pressing a special spirulina tablet, which comprises the following steps that: spirulina powder is crushed to be between 200 and 600 meshes and then is paved, the thickness of the spirulina powder is between 0.5 and 1.5cm, and deionized water is sprayed evenly to ultrafine spirulina powder according to 3 to 8 percent of the weight of the spirulina powder; the spirulina powder sprayed evenly with water is placed in an environment with a temperature of between 10 and 26 DEG C and the humidity of between 45 and 65 percent for 18 to 28 hours to naturally volatilize moisture; then the drying is performed at a temperature of between 60 and 70 DEG C for 4 to 6 hours to obtain spirulina particles; and finally magnesium stearate which accounts for 0.05 to 0.3 percent of the weight of the spirulina particles is added into the spirulina particles to directly press a special tablet. The method has the advantages of simple preparation technology, small using amount of excipients, small volume and low cost; the special spirulina tablet obtained by the preparation has the advantages of unique appearance, elegant tablet pattern, fine and smooth tablet surfaces, luster, even tablet weight and qualified friability, and various indexes all reach related regulations; and the special spirulina tablet is easy for a human body to absorb, ensures that a patient is easy to accept, and can remarkably improve sales profit.

Description

technical field [0001] The invention belongs to the field of pharmacy, and in particular relates to a method for pressing special-shaped spirulina tablets. Background technique [0002] Spirulina is a kind of multicellular filamentous cyanobacteria, which belongs to lower aquatic organisms. It likes to grow in high temperature and alkaline environment. It is named for its spiral filament. According to the size of algal filaments, the length of the screw pitch, and the different ecological habits, Spirulina can be divided into more than 30 species. At present, the more common ones are Spirulina platensis and Spirulina maxima. It mainly grows in lakes with high saline content. [0003] Spirulina is rich in various nutrients, its protein content reaches 70%, 3 times higher than that of beef, and its amino acid composition has reached the ideal protein standard determined by the Food and Agriculture Organization of the United Nations. In particular, the rich lysine, threonine...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/02A61K9/20A61P15/14A61P17/16A61P37/04A61P39/00
Inventor 彭江晨
Owner 溧阳市天目湖保健品有限公司
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